2N2K

Ensemble structure of the closed state of Lys63-linked diubiquitin in the absence of a ligand

Summary for 2N2K

Related1UBQ 3H7P
Descriptorubiquitin, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate (3 entities in total)
Functional Keywordspolyubiquitin, ensemble structure, protein dynamics, ubiquitin signaling, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationUbiquitin: Cytoplasm  P0CG48 P0CG48
Total number of polymer chains2
Total molecular weight17103.79
Authors
Liu, Z.,Gong, Z.,Tang, C. (deposition date: 2015-05-10, release date: 2015-07-08, Last modification date: 2015-09-23)
Primary citation
Liu, Z.,Gong, Z.,Jiang, W.X.,Yang, J.,Zhu, W.K.,Guo, D.C.,Zhang, W.P.,Liu, M.L.,Tang, C.
Lys63-linked ubiquitin chain adopts multiple conformational states for specific target recognition.
Elife, 4:-, 2015
PubMed: 26090905 (PDB entries with the same primary citation)
DOI: 10.7554/eLife.05767
MImport into Mendeley
Experimental method
SOLUTION NMR
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Structure validation

ClashscoreRamachandran outliersSidechain outliers10.2%33.0%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation report