2NN6
Structure of the human RNA exosome composed of Rrp41, Rrp45, Rrp46, Rrp43, Mtr3, Rrp42, Csl4, Rrp4, and Rrp40
Summary for 2NN6
Entry DOI | 10.2210/pdb2nn6/pdb |
Descriptor | Polymyositis/scleroderma autoantigen 1, Exosome complex exonuclease RRP41, Exosome complex exonuclease RRP43, ... (9 entities in total) |
Functional Keywords | rna, exosome, pm/scl, exoribonuclease, phosphorolytic, ribonuclease, hydrolase-transferase complex, hydrolase/transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q9NPD3 Q96B26 Q9NQT5 Q13868 Nucleus, nucleolus: Q9NQT4 Q15024 Q9Y3B2 Cytoplasm (Probable): Q5RKV6 |
Total number of polymer chains | 9 |
Total formula weight | 272665.69 |
Authors | Lima, C.D. (deposition date: 2006-10-23, release date: 2006-12-26, Last modification date: 2023-12-27) |
Primary citation | Liu, Q.,Greimann, J.C.,Lima, C.D. Reconstitution, activities, and structure of the eukaryotic RNA exosome. Cell(Cambridge,Mass.), 127:1223-1237, 2006 Cited by PubMed: 17174896DOI: 10.1016/j.cell.2006.10.037 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.35 Å) |
Structure validation
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