2M0Z
 
 | | cis form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative | | 分子名称: | 3,3'-(E)-diazene-1,2-diylbis{6-[(chloroacetyl)amino]benzenesulfonic acid}, Tyrosine-protein phosphatase non-receptor type 13 | | 著者 | Walser, R, Zerbe, O, Hamm, P. | | 登録日 | 2012-11-09 | | 公開日 | 2013-07-03 | | 最終更新日 | 2013-08-07 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Kinetic response of a photoperturbed allosteric protein.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4OT3
 | | Crystal structure of the S505L mutant of TAL effector dHax3 | | 分子名称: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 | | 著者 | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | | 登録日 | 2014-02-13 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.944 Å) | | 主引用文献 | Revisiting the TALE repeat
Protein Cell, 5, 2014
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2MBZ
 | | Structural Basis of a Thiopeptide Antibiotic Multidrug Resistance System from Streptomyces lividans:Promothiocin A in Complex with TipAS | | 分子名称: | HTH-type transcriptional activator TipA, Promothiocin A | | 著者 | Habazettl, J, Allan, M.G, Jensen, P, Sass, H, Grzesiek, S. | | 登録日 | 2013-08-12 | | 公開日 | 2014-12-10 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis and dynamics of multidrug recognition in a minimal bacterial multidrug resistance system.
Proc. Natl. Acad. Sci. U.S.A., 111, 2014
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6O1K
 | | Architectural principles for Hfq/Crc-mediated regulation of gene expression. Hfq-Crc-amiE 2:2:2 complex (core complex) | | 分子名称: | Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq | | 著者 | Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F. | | 登録日 | 2019-02-20 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | Architectural principles for Hfq/Crc-mediated regulation of gene expression
Elife, 8, 2019
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6NN6
 | | Structure of Dot1L-H2BK120ub nucleosome complex | | 分子名称: | DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ... | | 著者 | Anderson, C.J, Baird, M.R, Hsu, A, Barbour, E.H, Koyama, Y, Borgnia, M.J, McGinty, R.K. | | 登録日 | 2019-01-14 | | 公開日 | 2019-02-13 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase.
Cell Rep, 26, 2019
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2MKJ
 | | Solution structure of tandem RRM domains of cytoplasmic polyadenylation element binding protein 4 (CPEB4) in free state | | 分子名称: | Cytoplasmic polyadenylation element-binding protein 4 | | 著者 | Afroz, T, Skrisovska, L, Belloc, E, Boixet, J.G, Mendez, R, Allain, F.H.-T. | | 登録日 | 2014-02-07 | | 公開日 | 2014-07-23 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins
Genes Dev., 28, 2014
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4LXS
 | | Structure of the Toll - Spatzle complex, a molecular hub in Drosophila development and innate immunity (glycosylated form) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Stelter, M, Parthier, C, Breithaupt, C, Stubbs, M.T. | | 登録日 | 2013-07-30 | | 公開日 | 2014-04-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of the Toll-Spatzle complex, a molecular hub in Drosophila development and innate immunity.
Proc.Natl.Acad.Sci.USA, 111, 2014
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2M8L
 | | HIV capsid dimer structure | | 分子名称: | Capsid protein p24 | | 著者 | Deshmukh, L, Schwieters, C.D, Grishaev, A, Clore, G, Ghirlando, R. | | 登録日 | 2013-05-23 | | 公開日 | 2013-11-20 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR, SOLUTION SCATTERING | | 主引用文献 | Structure and Dynamics of Full-Length HIV-1 Capsid Protein in Solution.
J.Am.Chem.Soc., 135, 2013
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2MLO
 | | Human CCR2 Membrane-Proximal C-Terminal Region (PRO-C) in a Membrane bound form | | 分子名称: | MCP-1 receptor | | 著者 | Esaki, K, Yoshinaga, S, Tsuji, T, Toda, E, Terashima, Y, Saitoh, T, Kohda, D, Kohno, T, Osawa, M, Ueda, T, Shimada, I, Matsushima, K, Terasawa, H. | | 登録日 | 2014-03-04 | | 公開日 | 2014-10-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for the binding of the membrane-proximal C-terminal region of chemokine receptor CCR2 with the cytosolic regulator FROUNT.
Febs J., 281, 2014
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6NOX
 | | Solution structure of SFTI-KLK5 inhibitor | | 分子名称: | SFTI-KLK5 Peptide | | 著者 | White, A.M. | | 登録日 | 2019-01-16 | | 公開日 | 2019-04-03 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Amino Acid Scanning at P5' within the Bowman-Birk Inhibitory Loop Reveals Specificity Trends for Diverse Serine Proteases.
J. Med. Chem., 62, 2019
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4LQI
 | | Yeast 20S Proteasome in complex with Vibralactone | | 分子名称: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | | 著者 | List, A, Zeiler, E, Gallastegui, N, Rusch, M, Hedberg, C, Sieber, S.A, Groll, M. | | 登録日 | 2013-07-18 | | 公開日 | 2013-12-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Omuralide and Vibralactone: Differences in the Proteasome-beta-Lactone-gamma-Lactam Binding Scaffold Alter Target Preferences.
Angew.Chem.Int.Ed.Engl., 53, 2014
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4LU6
 | | Thermostabilized RebH | | 分子名称: | Flavin-dependent tryptophan halogenase RebH, PHOSPHATE ION | | 著者 | Poor, C.B, Lewis, J.C. | | 登録日 | 2013-07-24 | | 公開日 | 2014-06-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Improving the Stability and Catalyst Lifetime of the Halogenase RebH By Directed Evolution.
Chembiochem, 15, 2014
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2MGW
 | | Solution Structure of the UBA Domain of Human NBR1 | | 分子名称: | Next to BRCA1 gene 1 protein | | 著者 | Walinda, E, Morimoto, D, Sugase, K, Komatsu, M, Tochio, H, Shirakawa, M. | | 登録日 | 2013-11-09 | | 公開日 | 2014-04-09 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the ubiquitin-associated (UBA) domain of human autophagy receptor NBR1 and its interaction with ubiquitin and polyubiquitin.
J.Biol.Chem., 289, 2014
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2MM3
 | | Solution NMR structure of the ternary complex of human ileal bile acid-binding protein with glycocholate and glycochenodeoxycholate | | 分子名称: | GLYCOCHENODEOXYCHOLIC ACID, GLYCOCHOLIC ACID, Gastrotropin | | 著者 | Horvath, G, Egyed, O, Bencsura, A, Simon, A, Tochtrop, G.P, DeKoster, G.T, Covey, D.F, Cistola, D.P, Toke, O. | | 登録日 | 2014-03-07 | | 公開日 | 2014-05-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural determinants of ligand binding in the ternary complex of human ileal bile acid binding protein with glycocholate and glycochenodeoxycholate obtained from solution NMR
FEBS J., 283, 2016
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4N5Z
 | | Crystal structure of aerosol transmissible influenza H5 hemagglutinin mutant (N158D, N224K, Q226L and T318I) from the influenza virus A/Viet Nam/1203/2004 (H5N1) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | 著者 | Zhu, X, Wilson, I.A. | | 登録日 | 2013-10-10 | | 公開日 | 2013-11-20 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.9537 Å) | | 主引用文献 | Hemagglutinin Receptor Specificity and Structural Analyses of Respiratory Droplet-Transmissible H5N1 Viruses.
J.Virol., 88, 2014
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2LXN
 | | Solution NMR structure of glutamine amido transferase subunit of gaunosine monophosphate synthetase from Methanocaldococcus jannaschii | | 分子名称: | GMP synthase [glutamine-hydrolyzing] subunit A | | 著者 | Ali, R, Kumar, S, Balaram, H, Sarma, S.P. | | 登録日 | 2012-08-30 | | 公開日 | 2013-06-12 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | 1H, 13C, 15N assignment and secondary structure determination of glutamine amido transferase subunit of gaunosine monophosphate synthetase from Methanocaldococcus jannaschii
Biomol.Nmr Assign., 6, 2012
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6NXE
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4NNU
 | | Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation | | 分子名称: | DNA1, DNA2, Transcription factor A, ... | | 著者 | Ngo, H.B, Lovely, G.A, Phillips, R, Chan, D.C. | | 登録日 | 2013-11-19 | | 公開日 | 2014-01-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation.
Nat Commun, 5, 2014
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6O00
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2MC0
 | | Structural Basis of a Thiopeptide Antibiotic Multidrug Resistance System from Streptomyces lividans:Nosiheptide in Complex with TipAS | | 分子名称: | 4-(hydroxymethyl)-3-methyl-1H-indole-2-carboxylic acid, HTH-type transcriptional activator TipA, nosiheptide | | 著者 | Habazettl, J, Allan, M.G, Jensen, P, Sass, H, Grzesiek, S. | | 登録日 | 2013-08-12 | | 公開日 | 2014-12-10 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis and dynamics of multidrug recognition in a minimal bacterial multidrug resistance system
Proc.Natl.Acad.Sci.USA, 111, 2014
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6NZW
 | | LRRC8A-DCPIB in MSP1E3D1 nanodisc constricted state | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 4-{[(2S)-2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl]oxy}butanoic acid, Volume-regulated anion channel subunit LRRC8A | | 著者 | Kern, D.M, Hite, R.K, Brohawn, S.G. | | 登録日 | 2019-02-14 | | 公開日 | 2019-02-27 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs.
Elife, 8, 2019
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4NO6
 | | yCP in complex with Z-Leu-Leu-Leu-vinylsulfone | | 分子名称: | MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(3S)-5-methyl-1-(methylsulfonyl)hexan-3-yl]-L-leucinamide, Probable proteasome subunit alpha type-7, ... | | 著者 | Stein, M.L, Cui, H, Beck, P, Dubiella, C, Voss, C, Krueger, A, Schmidt, B, Groll, M. | | 登録日 | 2013-11-19 | | 公開日 | 2014-02-12 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the alpha-Ketoamide Electrophile as an Auspicious Reversible Lead Motif.
Angew.Chem.Int.Ed.Engl., 53, 2014
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6O38
 | | Structure of a chaperone-substrate complex | | 分子名称: | Acinetobacter secreted protease CpaA, SULFATE ION, Type II secretion chaperone CpaB, ... | | 著者 | Urusova, D.V, Tolia, N.H. | | 登録日 | 2019-02-26 | | 公開日 | 2019-07-24 | | 最終更新日 | 2019-09-25 | | 実験手法 | X-RAY DIFFRACTION (2.595 Å) | | 主引用文献 | The structure ofAcinetobacter-secreted protease CpaA complexed with its chaperone CpaB reveals a novel mode of a T2SS chaperone-substrate interaction.
J.Biol.Chem., 294, 2019
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2MJ5
 | | Structure of the UBA Domain of Human NBR1 in Complex with Ubiquitin | | 分子名称: | Next to BRCA1 gene 1 protein, Polyubiquitin-C | | 著者 | Walinda, E, Morimoto, D, Sugase, K, Komatsu, M, Tochio, H, Shirakawa, M. | | 登録日 | 2013-12-25 | | 公開日 | 2014-04-09 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the ubiquitin-associated (UBA) domain of human autophagy receptor NBR1 and its interaction with ubiquitin and polyubiquitin.
J.Biol.Chem., 289, 2014
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6O85
 | | Electron cryo-microscopy of the eukaryotic translation initiation factor 2B bound to eukaryotic translation initiation factor 2 from Homo sapiens | | 分子名称: | 2-(4-chloranylphenoxy)-~{N}-[4-[2-(4-chloranylphenoxy)ethanoylamino]cyclohexyl]ethanamide, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, ... | | 著者 | Nguyen, H.C, Kenner, L.R, Frost, A.S. | | 登録日 | 2019-03-08 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.
Science, 364, 2019
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