Cryo-EM Reconstruction of Protease-Activateable Adeno-Associated Virus 9 (AAV9-L001)

This is a large structure.

Summary for 6NXE

EMDB information0535
DescriptorCapsid protein VP1 (1 entity in total)
Functional Keywordsaav, activatable, gene therapy, provector, virus
Biological sourceAdeno-associated virus
Total number of polymer chains60
Total molecular weight3656350.08
Bennett, A.B.,Agbandje-Mckenna, M. (deposition date: 2019-02-08, release date: 2019-03-13, Last modification date: 2019-03-20)
Primary citation
Guenther, C.M.,Brun, M.J.,Bennett, A.D.,Ho, M.L.,Chen, W.,Zhu, B.,Lam, M.,Yamagami, M.,Kwon, S.,Bhattacharya, N.,Sousa, D.,Evans, A.C.,Voss, J.,Sevick-Muraca, E.M.,Agbandje-McKenna, M.,Suh, J.
Protease-Activatable Adeno-Associated Virus Vector for Gene Delivery to Damaged Heart Tissue.
Mol. Ther., 27:611-622, 2019
PubMed: 30772143 (PDB entries with the same primary citation)
DOI: 10.1016/j.ymthe.2019.01.015
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers18 0.9% 4.9%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

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