2MBZ
Structural Basis of a Thiopeptide Antibiotic Multidrug Resistance System from Streptomyces lividans:Promothiocin A in Complex with TipAS
Summary for 2MBZ
Entry DOI | 10.2210/pdb2mbz/pdb |
Related | 1NY9 |
NMR Information | BMRB: 19421 |
Related PRD ID | PRD_001255 |
Descriptor | HTH-type transcriptional activator TipA, Promothiocin A (2 entities in total) |
Functional Keywords | tipas/promothiocin a, protein/antibiotic, protein/thiopeptide, multidrug recognition, transcriptional activator, transcription activator-antibiotic complex, transcription activator/antibiotic |
Biological source | Streptomyces lividans More |
Total number of polymer chains | 2 |
Total formula weight | 17526.11 |
Authors | Habazettl, J.,Allan, M.G.,Jensen, P.,Sass, H.,Grzesiek, S. (deposition date: 2013-08-12, release date: 2014-12-10, Last modification date: 2023-11-15) |
Primary citation | Habazettl, J.,Allan, M.,Jensen, P.R.,Sass, H.J.,Thompson, C.J.,Grzesiek, S. Structural basis and dynamics of multidrug recognition in a minimal bacterial multidrug resistance system. Proc. Natl. Acad. Sci. U.S.A., 111:E5498-E5507, 2014 Cited by PubMed: 25489067DOI: 10.1073/pnas.1412070111 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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