2MJ5

Structure of the UBA Domain of Human NBR1 in Complex with Ubiquitin

Summary for 2MJ5

• Entry DOI: 10.2210/pdb2mj5/pdb
• Related: 1D3Z 2mgw
• Descriptor: Polyubiquitin-C, Next to BRCA1 gene 1 protein (2 entities in total)
• Functional Keywords: autophagy, protein degradation, ubiquitin binding, protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Ubiquitin: Cytoplasm (By similarity): P0CG48; Cytoplasm: Q14596
• Total number of polymer chains: 2
• Total formula weight: 14495.61

Authors

Walinda, E.,Morimoto, D.,Sugase, K.,Komatsu, M.,Tochio, H.,Shirakawa, M. (deposition date: 2013-12-25, release date: 2014-04-09, Last modification date: 2023-06-14)

• Primary citation: Walinda, E.,Morimoto, D.,Sugase, K.,Konuma, T.,Tochio, H.,Shirakawa, M.; Solution structure of the ubiquitin-associated (UBA) domain of human autophagy receptor NBR1 and its interaction with ubiquitin and polyubiquitin.; J.Biol.Chem., 289:13890-13902, 2014; PubMed: 24692539; DOI: 10.1074/jbc.M114.555441

Experimental method

SOLUTION NMR