PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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6KIU	Cryo-EM structure of human MLL1-ubNCP complex (3.2 angstrom) 分子名称: DNA (145-MER), GLUTAMINE, Histone H2A, ... 著者 Huang, J, Xue, H, Yao, T. 登録日 2019-07-20 公開日 2019-09-11 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
1S6Q	CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R147681 分子名称: 4-[4-(2,4,6-TRIMETHYL-PHENYLAMINO)-PYRIMIDIN-2-YLAMINO]-BENZONITRILE, POL polyprotein [Contains: Reverse transcriptase] 著者 Das, K, Arnold, E. 登録日 2004-01-26 公開日 2004-05-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 Variants. J.Med.Chem., 47, 2004
6KIW	Cryo-EM structure of human MLL3-ubNCP complex (4.0 angstrom) 分子名称: DNA (144-MER), DNA (145-MER), Histone H2A, ... 著者 Huang, J, Xue, H, Yao, T. 登録日 2019-07-20 公開日 2019-09-11 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
6KIZ	Cryo-EM structure of human MLL1-NCP complex, binding mode2 分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ... 著者 Huang, J, Xue, H, Yao, T. 登録日 2019-07-20 公開日 2019-09-11 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
6KIX	Cryo-EM structure of human MLL1-NCP complex, binding mode1 分子名称: DNA (145-MER), GLUTAMINE, Histone H2A, ... 著者 Huang, J, Xue, H, Yao, T. 登録日 2019-07-20 公開日 2019-09-11 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
1SUQ	CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R185545 分子名称: (6-[4-(AMINOMETHYL)-2,6-DIMETHYLPHENOXY]-2-{[4-(AMINOMETHYL)PHENYL]AMINO}-5-BROMOPYRIMIDIN-4-YL)METHANOL, MAGNESIUM ION, REVERSE TRANSCRIPTASE 著者 Das, K, Arnold, E. 登録日 2004-03-26 公開日 2004-05-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 Variants J.Med.Chem., 47, 2004
1MN7	NDP kinase mutant (H122G;N119S;F64W) in complex with aBAZTTP 分子名称: 3'-AZIDO-3'-DEOXY-THYMIDINE-5'-ALPHA BORANO TRIPHOSPHATE, MAGNESIUM ION, NDP kinase 著者 gallois-montbrun, s, schneider, b, chen, y, giacomoni-fernandes, v, mulard, l, morera, s, janin, j, deville-bonne, d, veron, m. 登録日 2002-09-05 公開日 2002-10-02 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Improving nucleoside diphosphate kinase for antiviral nucleotide analogs activation J.BIOL.CHEM., 277, 2002
5DCA	Crystal structure of yeast full length Brr2 in complex with Prp8 Jab1 domain 分子名称: Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2 著者 Absmeier, E, Wollenhaupt, J, Santos, K.F, Wahl, M.C. 登録日 2015-08-23 公開日 2015-12-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation. Genes Dev., 29, 2015
6ESH	Nucleosome breathing : Class 3 分子名称: DNA (137-MER), Histone H2A, Histone H2B 1.1, ... 著者 Bilokapic, S, Halic, M. 登録日 2017-10-20 公開日 2017-12-20 最終更新日 2025-07-09 実験手法 ELECTRON MICROSCOPY (5.1 Å) 主引用文献 Histone octamer rearranges to adapt to DNA unwrapping. Nat. Struct. Mol. Biol., 25, 2018
6ESI	Nucleosome breathing : Class 4 分子名称: DNA (133-MER), Histone H2A, Histone H2B 1.1, ... 著者 Bilokapic, S, Halic, M. 登録日 2017-10-20 公開日 2017-12-20 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (6.3 Å) 主引用文献 Histone octamer rearranges to adapt to DNA unwrapping. Nat. Struct. Mol. Biol., 25, 2018
7PB4	Cenp-HIK 3-protein complex 分子名称: Centromere protein H, Centromere protein I, Centromere protein K 著者 Bellini, D, Yatskevich, S, Muir, W.K, Barford, D. 登録日 2021-07-30 公開日 2022-04-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
1U2Z	Crystal structure of histone K79 methyltransferase Dot1p from yeast 分子名称: Histone-lysine N-methyltransferase, H3 lysine-79 specific, S-ADENOSYL-L-HOMOCYSTEINE 著者 Sawada, K, Yang, Z, Horton, J.R, Collins, R.E, Zhang, X, Cheng, X. 登録日 2004-07-20 公開日 2004-09-07 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase J.Biol.Chem., 279, 2004
7R5S	Structure of the human CCAN bound to alpha satellite DNA 分子名称: Centromere protein H, Centromere protein I, Centromere protein K, ... 著者 Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. 登録日 2022-02-11 公開日 2022-04-27 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.83 Å) 主引用文献 Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
7R5V	Structure of the human CCAN CENP-A alpha-satellite complex 分子名称: Centromere protein H, Centromere protein I, Centromere protein K, ... 著者 Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. 登録日 2022-02-11 公開日 2022-04-27 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (4.55 Å) 主引用文献 Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
5B40	The nucleosome structure containing H2B-K120 and H4-K31 monoubiquitinations 分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Machida, S, Sekine, S, Nishiyama, Y, Horikoshi, N, Kurumizaka, H. 登録日 2016-03-22 公開日 2016-06-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.33 Å) 主引用文献 Monoubiquitination of histones H2B and H4 changes the nucleosome stability without affecting the nucleosome structure To Be Published
4LNL	Structure of Escherichia coli Threonine Aldolase in Complex with Allo-Thr 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Low-specificity L-threonine aldolase, ... 著者 Safo, M.K. 登録日 2013-07-11 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 On the catalytic mechanism and stereospecificity of Escherichia coli l-threonine aldolase. Febs J., 281, 2014
4LNJ	Structure of Escherichia coli Threonine Aldolase in Unliganded Form 分子名称: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Low-specificity L-threonine aldolase, ... 著者 Safo, M.K, Contestabile, R, Remesh, S.G. 登録日 2013-07-11 公開日 2013-11-06 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 On the catalytic mechanism and stereospecificity of Escherichia coli l-threonine aldolase. Febs J., 281, 2014
4LNM	Structure of Escherichia coli Threonine Aldolase in Complex with Serine 分子名称: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Safo, M.K, Contestabile, R, Remesh, S.G. 登録日 2013-07-11 公開日 2013-11-06 最終更新日 2024-12-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 On the catalytic mechanism and stereospecificity of Escherichia coli l-threonine aldolase. Febs J., 281, 2014
1L9K	dengue methyltransferase 分子名称: RNA-DIRECTED RNA POLYMERASE, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION 著者 Egloff, M.P, Benarroch, D, Selisko, B, Romette, J.L, Canard, B. 登録日 2002-03-25 公開日 2003-03-25 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 An RNA cap (nucleoside-2'-O-) methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization Embo J., 21, 2002
1PF7	CRYSTAL STRUCTURE OF HUMAN PNP COMPLEXED WITH IMMUCILLIN H 分子名称: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION 著者 De Azevedo Jr, W.F, Canduri, F, Dos Santos, D.M, Pereira, J.H, Dias, M.V.B, Silva, R.G, Mendes, M.A, Palma, M.S, Basso, L.A, Santos, D.S. 登録日 2003-05-24 公開日 2004-06-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for inhibition of human PNP by immucillin-H Biochem.Biophys.Res.Commun., 309, 2003
1SV5	CRYSTAL STRUCTURE OF K103N MUTANT HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R165335 分子名称: 4-({6-AMINO-5-BROMO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE, Reverse Transcriptase 著者 Das, K, Arnold, E. 登録日 2004-03-27 公開日 2004-05-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 Variants J.Med.Chem., 47, 2004
4Z2N	Crystal structure of human FACT SPT16 middle domain 分子名称: FACT complex subunit SPT16 著者 Tsunaka, Y, Fujiwara, Y, Oyama, T, Hirose, S, Morikawa, K. 登録日 2015-03-30 公開日 2016-03-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.923 Å) 主引用文献 Integrated molecular mechanism directing nucleosome reorganization by human FACT. Genes Dev., 30, 2016
3SIV	Structure of a hPrp31-15.5K-U4atac 5' stem loop complex, dimeric form 分子名称: NHP2-like protein 1, U4/U6 small nuclear ribonucleoprotein Prp31, U4atac snRNA 著者 Liu, S, Ghalei, H, Luhrmann, R, Wahl, M.C. 登録日 2011-06-20 公開日 2011-08-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.304 Å) 主引用文献 Structural basis for the dual U4 and U4atac snRNA-binding specificity of spliceosomal protein hPrp31. Rna, 17, 2011
2BAN	Crystal structure of HIV-1 reverse transcriptase (RT) in complex with JANSSEN-R157208 分子名称: 5-ETHYL-3-[(2-METHOXYETHYL)METHYLAMINO]-6-METHYL-4-(3-METHYLBENZYL)PYRIDIN-2(1H)-ONE, MANGANESE (II) ION, Reverse transcriptase P51 subunit, ... 著者 Das, K, Arnold, E. 登録日 2005-10-14 公開日 2005-12-06 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Crystal Structures for HIV-1 Reverse Transcriptase in Complexes with Three Pyridinone Derivatives: A New Class of Non-Nucleoside Inhibitors Effective against a Broad Range of Drug-Resistant Strains. J.Med.Chem., 48, 2005
4EB8	Crystal structure of purine nucleoside phosphorylase (W16Y, W94Y, W178Y, H257W) mutant from human complexed with DADMe-ImmG and phosphate 分子名称: 1,2-ETHANEDIOL, 2-amino-7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl]methyl}-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, PHOSPHATE ION, ... 著者 Ho, M.C, Haapalainen, A.M, Suarez, J.J, Almo, S.C, Schramm, V.L. 登録日 2012-03-23 公開日 2013-02-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Catalytic Site Conformations in Human PNP by (19)F-NMR and Crystallography. Chem.Biol., 20, 2013

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