5DCA

Crystal structure of yeast full length Brr2 in complex with Prp8 Jab1 domain

Summary for 5DCA

• Entry DOI: 10.2210/pdb5dca/pdb
• Descriptor: Pre-mRNA-splicing helicase BRR2, Pre-mRNA-splicing factor 8 (3 entities in total)
• Functional Keywords: protein complex, helicase, rnp remodeling, spliceosome activation, hydrolase
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Cellular location: Nucleus : P32639 P33334
• Total number of polymer chains: 2
• Total formula weight: 250657.74

Authors

Absmeier, E.,Wollenhaupt, J.,Santos, K.F.,Wahl, M.C. (deposition date: 2015-08-23, release date: 2015-12-16, Last modification date: 2024-01-10)

• Primary citation: Absmeier, E.,Wollenhaupt, J.,Mozaffari-Jovin, S.,Becke, C.,Lee, C.T.,Preussner, M.,Heyd, F.,Urlaub, H.,Luhrmann, R.,Santos, K.F.,Wahl, M.C.; The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation.; Genes Dev., 29:2576-2587, 2015; PubMed: 26637280; DOI: 10.1101/gad.271528.115

Experimental method

X-RAY DIFFRACTION (2.8 Å)