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5DCA

Crystal structure of yeast full length Brr2 in complex with Prp8 Jab1 domain

Functional Information from GO Data
ChainGOidnamespacecontents
A0000388biological_processspliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
A0000398biological_processmRNA splicing, via spliceosome
A0003676molecular_functionnucleic acid binding
A0003724molecular_functionRNA helicase activity
A0004386molecular_functionhelicase activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005681cellular_componentspliceosomal complex
A0005682cellular_componentU5 snRNP
A0006397biological_processmRNA processing
A0008380biological_processRNA splicing
A0016787molecular_functionhydrolase activity
A0016887molecular_functionATP hydrolysis activity
A0042802molecular_functionidentical protein binding
A0046540cellular_componentU4/U6 x U5 tri-snRNP complex
J0000398biological_processmRNA splicing, via spliceosome
J0005681cellular_componentspliceosomal complex
J0008233molecular_functionpeptidase activity
J0008237molecular_functionmetallopeptidase activity
Functional Information from PROSITE/UniProt
site_idPS00012
Number of Residues16
DetailsPHOSPHOPANTETHEINE Phosphopantetheine attachment site. GINIDSLKFNELVKLM
ChainResidueDetails
AGLY174-MET189

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00541
ChainResidueDetails
ATRP612
AGLN1461

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198
ChainResidueDetails
ASER494

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PDB entries from 2024-07-24

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