PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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3WLK	Crystal structure of barley beta-D-glucan glucohydrolase isoenzyme EXO1 in complex with 4-deoxy-glucose 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-D-glucan exohydrolase isoenzyme ExoI, GLYCEROL, ... 著者 Streltsov, V.A, Hrmova, M. 登録日 2013-11-12 公開日 2015-03-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of processive catalysis by an exo-hydrolase with a pocket-shaped active site. Nat Commun, 10, 2019
7E46	Structure of the CYP102A1 Haem Domain with N-Carboxybenzyl-L-Prolyl-L-Phenylalanine in complex with (S)-(-)-1-Phenylethylamine 分子名称: (1S)-1-phenylethanamine, (2S)-3-phenyl-2-[[(2S)-1-phenylmethoxycarbonylpyrrolidin-2-yl]carbonylamino]propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, ... 著者 Stanfield, J.K, Sugimoto, H, Shoji, O. 登録日 2021-02-10 公開日 2022-02-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Structure of the CYP102A1 Haem Domain with N-Carboxybenzyl-L-Prolyl-L-Phenylalanine in complex with (S)-(-)-1-Phenylethylamine at 1.91 Angstrom Resolution To Be Published
8FYH	G4 RNA-mediated PRC2 dimer 分子名称: G4 RNA, Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH2, ... 著者 Song, J, Kasinath, V. 登録日 2023-01-26 公開日 2023-10-04 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis for inactivation of PRC2 by G-quadruplex RNA. Science, 381, 2023
4EJH	Human Cytochrome P450 2A13 in complex with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) 分子名称: 4-[methyl(nitroso)amino]-1-(pyridin-3-yl)butan-1-one, Cytochrome P450 2A13, GLYCEROL, ... 著者 DeVore, N.M, Scott, E.E. 登録日 2012-04-06 公開日 2012-06-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone binding and access channel in human cytochrome P450 2A6 and 2A13 enzymes. J.Biol.Chem., 287, 2012
4EMS	Crystal Structure Analysis of Coniferyl Alcohol 9-O-Methyltransferase from Linum Nodiflorum 分子名称: Coniferyl alcohol 9-O-methyltransferase, GLYCEROL 著者 Wolters, S, Heine, A, Petersen, M. 登録日 2012-04-12 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7534 Å) 主引用文献 Structural analysis of coniferyl alcohol 9-O-methyltransferase from Linum nodiflorum reveals a novel active-site environment. Acta Crystallogr.,Sect.D, 69, 2013
6F6Z	Mouse Thymidylate Synthase Cocrystallized with N(4)OHdCMP and Soaked in Methylenetetrahydrofolate 分子名称: (2~{S})-2-[[4-[[(6~{R})-2-azanyl-4-oxidanylidene-5,6,7,8-tetrahydro-1~{H}-pteridin-6-yl]methyl-methyl-amino]phenyl]carbonylamino]pentanedioic acid, 2'-deoxy-N-hydroxycytidine 5'-(dihydrogen phosphate), Thymidylate synthase 著者 Wilk, P, Jarmula, A, Maj, P, Rode, W. 登録日 2017-12-06 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.127 Å) 主引用文献 Molecular Mechanism of Thymidylate Synthase Inhibition by N4-Hydroxy-dCMP in View of Spectrophotometric and Crystallographic Studies Int J Mol Sci, 22, 2021
6FBV	Single particle cryo em structure of Mycobacterium tuberculosis RNA polymerase in complex with Fidaxomicin 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Das, K, Lin, W, Ebright, E. 登録日 2017-12-19 公開日 2018-02-28 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.52 Å) 主引用文献 Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3). Mol. Cell, 70, 2018
4D18	Crystal structure of the COP9 signalosome 分子名称: COP9 SIGNALOSOME COMPLEX SUBUNIT 1, COP9 SIGNALOSOME COMPLEX SUBUNIT 2, COP9 SIGNALOSOME COMPLEX SUBUNIT 3, ... 著者 Bunker, R.D, Lingaraju, G.M, Thoma, N.H. 登録日 2014-05-01 公開日 2014-07-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (4.08 Å) 主引用文献 Crystal Structure of the Human Cop9 Signalosome Nature, 512, 2014
6F9B	Asymmetric unit of Rift Valley fever virus glycoprotein shell 分子名称: Glycoprotein 著者 Halldorsson, S, Bowden, T.A, Huiskonen, J.T. 登録日 2017-12-14 公開日 2018-01-31 最終更新日 2018-02-07 実験手法 ELECTRON MICROSCOPY (13.3 Å) 主引用文献 Shielding and activation of a viral membrane fusion protein. Nat Commun, 9, 2018
6ET9	Structure of the acetoacetyl-CoA-thiolase/HMG-CoA-synthase complex from Methanothermococcus thermolithotrophicus at 2.75 A 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Acetyl-CoA acetyltransferase thiolase, CHLORIDE ION, ... 著者 Engilberge, S, Voegeli, B, Girard, E, Riobe, F, Maury, O, Erb, T.J, Shima, S, Wagner, T. 登録日 2017-10-25 公開日 2018-03-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Archaeal acetoacetyl-CoA thiolase/HMG-CoA synthase complex channels the intermediate via a fused CoA-binding site. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4D10	Crystal structure of the COP9 signalosome 分子名称: COP9 SIGNALOSOME COMPLEX SUBUNIT 1, COP9 SIGNALOSOME COMPLEX SUBUNIT 2, COP9 SIGNALOSOME COMPLEX SUBUNIT 3, ... 著者 Bunker, R.D, Lingaraju, G.M, Thoma, N.H. 登録日 2014-04-30 公開日 2014-07-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Crystal Structure of the Human Cop9 Signalosome Nature, 512, 2014
6EYC	Re-refinement of the MCM2-7 double hexamer using ISOLDE 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, ... 著者 Croll, T.I. 登録日 2017-11-11 公開日 2018-06-20 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 ISOLDE: a physically realistic environment for model building into low-resolution electron-density maps. Acta Crystallogr D Struct Biol, 74, 2018
4DDF	Computationally Designed Self-assembling Octahedral Cage protein, O333, Crystallized in space group P4 分子名称: CHLORIDE ION, Propanediol utilization polyhedral body protein PduT, SULFATE ION 著者 Sawaya, M.R, King, N.P, Sheffler, W, Baker, D, Yeates, T.O. 登録日 2012-01-18 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Computational design of self-assembling protein nanomaterials with atomic level accuracy. Science, 336, 2012
6F3T	Crystal structure of the human TAF5-TAF6-TAF9 complex 分子名称: CHLORIDE ION, Transcription initiation factor TFIID subunit 5, Transcription initiation factor TFIID subunit 6, ... 著者 Haffke, M, Berger, I. 登録日 2017-11-28 公開日 2018-12-05 最終更新日 2018-12-19 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Chaperonin CCT checkpoint function in basal transcription factor TFIID assembly. Nat. Struct. Mol. Biol., 25, 2018
4DQL	Crystal structure of the FAD binding domain of cytochrome P450 BM3 in complex with NADP+ 分子名称: Bifunctional P-450/NADPH-P450 reductase, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 joyce, M.G, leys, D. 登録日 2012-02-16 公開日 2012-03-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The crystal structure of the FAD/NADPH-binding domain of flavocytochrome P450 BM3. Febs J., 279, 2012
8FHS	Human L-type voltage-gated calcium channel Cav1.2 in the presence of amiodarone and sofosbuvir at 3.3 Angstrom resolution 分子名称: (2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Gao, S, Yao, X, Yan, N. 登録日 2022-12-15 公開日 2023-12-13 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis for human Ca v 1.2 inhibition by multiple drugs and the neurotoxin calciseptine. Cell, 186, 2023
7ELM	Structure of Csy-AcrIF24 分子名称: AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ... 著者 Zhang, L, Feng, Y. 登録日 2021-04-12 公開日 2022-04-20 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.88 Å) 主引用文献 Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24. Nat Commun, 13, 2022
7ELN	Structure of Csy-AcrIF24-dsDNA 分子名称: 54-MER DNA, AcrIF24, CRISPR type I-F/YPEST-associated protein Csy2, ... 著者 Zhang, L, Feng, Y. 登録日 2021-04-12 公開日 2022-04-20 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24. Nat Commun, 13, 2022
4DJP	Crystal Structure of wild-type HIV-1 Protease in Complex with MKP73 分子名称: PHOSPHATE ION, Pol polyprotein, methyl (2S)-3-({[(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl][(2S)-2-methylbutyl]amino}-1-phenylbutan-2-yl]carbamoyl}oxy)-2-methylpropanoate 著者 Schiffer, C.A, Nalam, M.N.L. 登録日 2012-02-02 公開日 2012-08-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Design, synthesis, and biological and structural evaluations of novel HIV-1 protease inhibitors to combat drug resistance. J.Med.Chem., 55, 2012
4DJR	Crystal Structure of wild-type HIV-1 Protease in Complex with MKP97 分子名称: PHOSPHATE ION, Pol polyprotein, [(2S)-5-oxopyrrolidin-2-yl]methyl [(2S,3R)-4-{(1,3-benzothiazol-6-ylsulfonyl)[(2S)-2-methylbutyl]amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate 著者 Schiffer, C.A, Nalam, M.N.L. 登録日 2012-02-02 公開日 2012-08-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Design, synthesis, and biological and structural evaluations of novel HIV-1 protease inhibitors to combat drug resistance. J.Med.Chem., 55, 2012
8FKJ	Yeast ATP Synthase in conformation-3, at pH 6 分子名称: ATP synthase protein 8, ATP synthase subunit 4, mitochondrial, ... 著者 Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M. 登録日 2022-12-21 公開日 2024-01-24 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling. Nat.Struct.Mol.Biol., 31, 2024
8FHY	Crystal structure of the SARS-CoV-2 receptor binding domain in complex with neutralizing antibody WRAIR-5021 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, MALONATE ION, ... 著者 Sankhala, R.S, Jensen, J.L, Joyce, M.G. 登録日 2022-12-15 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques. Nat Commun, 15, 2024
4DQH	Crystal Structure of (R14C/E65C) HIV-1 Protease in complex with DRV 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, GLYCEROL, Wild-type HIV-1 protease dimer 著者 Schiffer, C.A, Mittal, S. 登録日 2012-02-15 公開日 2012-03-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Hydrophobic core flexibility modulates enzyme activity in HIV-1 protease. J.Am.Chem.Soc., 134, 2012
3UN4	Yeast 20S proteasome in complex with PR-957 (morpholine) 分子名称: 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol, Proteasome component C1, Proteasome component C11, ... 著者 Huber, E, Basler, M, Schwab, R, Heinemeyer, W, Kirk, C, Groettrup, M, Groll, M. 登録日 2011-11-15 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity. Cell(Cambridge,Mass.), 148, 2012
7DTI	Solution structure of the complex between RNA polymerase subunit RPB6 and TFIIH p62 PH domain 分子名称: DNA-directed RNA polymerases I, II, and III subunit RPABC2, ... 著者 Okuda, M, Nishimura, Y. 登録日 2021-01-05 公開日 2022-08-10 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Three human RNA polymerases interact with TFIIH via a common RPB6 subunit. Nucleic Acids Res., 50, 2022

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