8FYH

G4 RNA-mediated PRC2 dimer

Summary for 8FYH

• Entry DOI: 10.2210/pdb8fyh/pdb
• EMDB information: 29578 29647 29656
• Descriptor: Polycomb protein SUZ12, Polycomb protein EED, Histone-binding protein RBBP4, ... (8 entities in total)
• Functional Keywords: prc2, g-quadruplex rna, rnp complex, chromatin modifier, gene regulation
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 13
• Total formula weight: 929371.37

Authors

Song, J.,Kasinath, V. (deposition date: 2023-01-26, release date: 2023-10-04)

• Primary citation: Song, J.,Gooding, A.R.,Hemphill, W.O.,Love, B.D.,Robertson, A.,Yao, L.,Zon, L.I.,North, T.E.,Kasinath, V.,Cech, T.R.; Structural basis for inactivation of PRC2 by G-quadruplex RNA.; Science, 381:1331-1337, 2023; PubMed: 37733873; DOI: 10.1126/science.adh0059

Experimental method

ELECTRON MICROSCOPY (3.4 Å)