8FYH
G4 RNA-mediated PRC2 dimer
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, H | Polycomb protein SUZ12 | polymer | 739 | 83181.9 | 2 | UniProt (Q15022) Pfam (PF09733) In PDB | Homo sapiens (human) | Chromatin precipitated E2F target 9 protein,ChET 9 protein,Joined to JAZF1 protein,Suppressor of zeste 12 protein homolog |
2 | C, I | Polycomb protein EED | polymer | 441 | 50267.7 | 2 | UniProt (O75530) Pfam (PF00400) In PDB | Homo sapiens (human) | hEED,Embryonic ectoderm development protein,WD protein associating with integrin cytoplasmic tails 1,WAIT-1 |
3 | D, J | Histone-binding protein RBBP4 | polymer | 425 | 47709.5 | 2 | UniProt (Q09028) Pfam (PF12265) Pfam (PF00400) In PDB | Homo sapiens (human) | Chromatin assembly factor 1 subunit C,CAF-1 subunit C,Chromatin assembly factor I p48 subunit,CAF-I p48,Nucleosome-remodeling factor subunit RBAP48,Retinoblastoma-binding protein 4,RBBP-4,Retinoblastoma-binding protein p48 |
4 | A, G | Histone-lysine N-methyltransferase EZH2 | polymer | 751 | 86149.1 | 2 | UniProt (Q15910) Pfam (PF11616) Pfam (PF18118) Pfam (PF21358) Pfam (PF18264) Pfam (PF00856) In PDB | Homo sapiens (human) | ENX-1,Enhancer of zeste homolog 2,Lysine N-methyltransferase 6 |
5 | E, K | protein Jumonji isoform X3 | polymer | 1238 | 138406.2 | 2 | UniProt (A0A6I9KXB3) Pfam (PF02375) Pfam (PF01388) Pfam (PF02373) Pfam (PF02928) In PDB | Homo sapiens (human) | |
6 | F, L | Zinc finger protein AEBP2 | polymer | 517 | 54535.5 | 2 | UniProt (Q6ZN18) In PDB | Homo sapiens (human) | Adipocyte enhancer-binding protein 2,AE-binding protein 2 |
7 | M | G4 RNA | polymer | 24 | 7955.8 | 1 | Homo sapiens | ||
8 | G, A | ZINC ION | non-polymer | 65.4 | 14 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 13 |
Total formula weight | 928455.6 | |
Non-Polymers* | Number of molecules | 14 |
Total formula weight | 915.7 | |
All* | Total formula weight | 929371.4 |