PDB: 2005 件ウェブページステータス検索Chemie searchBIRD

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6ZTJ	E. coli 70S-RNAP expressome complex in NusG-coupled state (38 nt intervening mRNA) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ... 著者 Webster, M.W, Takacs, M, Weixlbaumer, A. 登録日 2020-07-20 公開日 2020-09-16 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis of transcription-translation coupling and collision in bacteria. Science, 369, 2020
3P8O	Crystal structure of HCV NS3/NS4A protease complexed with des-bromine analogue of BI 201335 分子名称: HCV non-structural protein 4A, HCV serine protease NS3, N-[(cyclopentyloxy)carbonyl]-3-methyl-L-valyl-(4R)-N-[(1R,2S)-1-carboxy-2-ethenylcyclopropyl]-4-[(7-methoxy-2-{2-[(2-methylpropanoyl)amino]-1,3-thiazol-4-yl}quinolin-4-yl)oxy]-L-prolinamide, ... 著者 Lemke, C.T. 登録日 2010-10-14 公開日 2011-01-26 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Combined X-ray, NMR, and kinetic analyses reveal uncommon binding characteristics of the hepatitis C virus NS3-NS4A protease inhibitor BI 201335. J.Biol.Chem., 286, 2011
2A4O	Dual modes of modification of Hepatitis A virus 3C protease by a serine derived beta-lactone: selective crytstallization and high resolution structure of the His102 adduct 分子名称: ACETYL GROUP, N-[(BENZYLOXY)CARBONYL]-L-ALANINE, PHENYLALANINE AMIDE, ... 著者 Yin, J, Bergmann, E.M, Cherney, M.M, Lall, M.S, Jain, R.P, Vederas, J.C, James, M.N.G. 登録日 2005-06-29 公開日 2005-12-27 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Dual Modes of Modification of Hepatitis A Virus 3C Protease by a Serine-derived beta-Lactone: Selective Crystallization and Formation of a Functional Catalytic Triad in the Active Site J.MOL.BIOL., 354, 2005
6S5V	Crystal structure of the Cap-Midlink region of the H5N1 Influenza A virus polymerase in complex with a Cap-domain binding analogue 分子名称: (1~{S},2~{S},3~{S},6~{R})-2-[[2-[5,7-bis(fluoranyl)-1~{H}-indol-3-yl]-5-fluoranyl-pyrimidin-4-yl]amino]-3,6-dimethyl-cyclohexane-1-carboxylic acid, GLYCEROL, POTASSIUM ION, ... 著者 Keown, J.R, Fodor, E, Grimes, J.M. 登録日 2019-07-02 公開日 2019-11-06 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Design, Synthesis, and Biological Evaluation of Novel Indoles Targeting the Influenza PB2 Cap Binding Region. J.Med.Chem., 62, 2019
1A1Q	HEPATITIS C VIRUS NS3 PROTEINASE 分子名称: NS3 PROTEINASE, ZINC ION 著者 Love, R.A, Parge, H.E, Wickersham, J.A, Hostomsky, Z, Habuka, N, Moomaw, E.W, Adachi, T, Hostomska, Z. 登録日 1997-12-12 公開日 1998-03-25 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site. Cell(Cambridge,Mass.), 87, 1996
1A1V	HEPATITIS C VIRUS NS3 HELICASE DOMAIN COMPLEXED WITH SINGLE STRANDED SDNA 分子名称: DNA (5'-D(*UP*UP*UP*UP*UP*UP*UP*U)-3'), PROTEIN (NS3 PROTEIN), SULFATE ION 著者 Kim, J.L, Morgenstern, K.A, Griffith, J.P, Dwyer, M.D, Thomson, J.A, Murcko, M.A, Lin, C, Caron, P.R. 登録日 1997-12-17 公開日 1999-01-13 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding. Structure, 6, 1998
1ZH1	Structure of the zinc-binding domain of HCV NS5A 分子名称: ZINC ION, non-structural polyprotein 著者 Tellinghuisen, T.L, Marcotrigiano, J, Rice, C.M. 登録日 2005-04-22 公開日 2005-05-24 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase. Nature, 435, 2005
1NN8	CryoEM structure of poliovirus receptor bound to poliovirus 分子名称: MYRISTIC ACID, coat protein VP1, coat protein VP2, ... 著者 He, Y, Mueller, S, Chipman, P.R, Bator, C.M, Peng, X, Bowman, V.D, Mukhopadhyay, S, Wimmer, E, Kuhn, R.J, Rossmann, M.G. 登録日 2003-01-13 公開日 2004-01-27 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (15 Å) 主引用文献 Complexes of poliovirus serotypes with their common cellular receptor, CD155 J.Virol., 77, 2003
2C8I	Complex Of Echovirus Type 12 With Domains 1, 2, 3 and 4 Of Its Receptor Decay Accelerating Factor (Cd55) By Cryo Electron Microscopy At 16 A 分子名称: COMPLEMENT DECAY-ACCELERATING FACTOR, ECHOVIRUS 11 COAT PROTEIN VP1, ECHOVIRUS 11 COAT PROTEIN VP2, ... 著者 Pettigrew, D.M, Williams, D.T, Kerrigan, D, Evans, D.J, Lea, S.M, Bhella, D. 登録日 2005-12-05 公開日 2006-01-17 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (14 Å) 主引用文献 Structural and Functional Insights Into the Interaction of Echoviruses and Decay-Accelerating Factor. J.Biol.Chem., 281, 2006
2HWK	Crystal Structure of Venezuelan Equine Encephalitis Alphavirus nsP2 Protease Domain 分子名称: FORMIC ACID, helicase nsP2 著者 Russo, A.T, White, M.A, Watowich, S.J. 登録日 2006-08-01 公開日 2006-09-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The Crystal Structure of the Venezuelan Equine Encephalitis Alphavirus nsP2 Protease. Structure, 14, 2006
5FX5	Novel inhibitors of human rhinovirus 3C protease 分子名称: GLYCEROL, RHINOVIRUS 3C PROTEASE, TETRAETHYLENE GLYCOL, ... 著者 Kawatkar, S, Ek, M, Hoesch, V, Gagnon, M, Nilsson, E, Lister, T, Olsson, L, Patel, J, Yu, Q. 登録日 2016-02-24 公開日 2016-06-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Design and Structure-Activity Relationships of Novel Inhibitors of Human Rhinovirus 3C Protease. Bioorg.Med.Chem.Lett., 26, 2016
1VRH	HRV14/SDZ 880-061 COMPLEX 分子名称: 2-[4-(2H-1,4-BENZOTHIAZINE-3-YL)-PIPERAZINE-1-LY]-1,3-THIAZOLE-4-CARBOXYLIC ACID ETHYLESTER, RHINOVIRUS 14 著者 Oren, D.A, Zhang, A, Arnold, E. 登録日 1996-02-26 公開日 1997-02-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Synthesis and activity of piperazine-containing antirhinoviral agents and crystal structure of SDZ 880-061 bound to human rhinovirus 14. J.Mol.Biol., 259, 1996
7WUV	CryoEM structure of sNS1 hexamer 分子名称: Core protein 著者 Shu, B, Ooi, J.S.G, Lok, S.M. 登録日 2022-02-09 公開日 2022-12-21 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever. Nat Commun, 13, 2022
7WUT	CryoEM structure of stable sNS1 tetramer 分子名称: Core protein 著者 Shu, B, Ooi, J.S.G, Lok, S.M. 登録日 2022-02-09 公開日 2022-12-21 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever. Nat Commun, 13, 2022
7WUU	CryoEM structure of loose sNS1 tetramer 分子名称: Core protein 著者 Shu, B, Lok, S.M. 登録日 2022-02-09 公開日 2022-12-21 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (8.3 Å) 主引用文献 CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever. Nat Commun, 13, 2022
7NBV	Structure of 2A protein from Theilers murine encephalomyelitis virus (TMEV) 分子名称: BROMIDE ION, Capsid protein VP0 著者 Hill, C.H, Cook, G.M, Napthine, S, Kibe, A, Brown, K, Caliskan, N, Firth, A.E, Graham, S.C, Brierley, I. 登録日 2021-01-28 公開日 2021-12-08 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Investigating molecular mechanisms of 2A-stimulated ribosomal pausing and frameshifting in Theilovirus. Nucleic Acids Res., 49, 2021
7V1J	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH and m7GpppA) 分子名称: Core protein, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7V1B	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH) 分子名称: CITRIC ACID, Core protein, ISOPROPYL ALCOHOL, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7V1H	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAM and m7GTP) 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, CITRIC ACID, Core protein, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
2XYA	Non-covalent inhibtors of rhinovirus 3C protease. 分子名称: 2-PHENYLQUINOLIN-4-OL, PICORNAIN 3C 著者 Petersen, J, Edman, K, Edfeldt, F, Johansson, C. 登録日 2010-11-16 公開日 2011-04-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Non-Covalent Inhibitors of Rhinovirus 3C Protease. Bioorg.Med.Chem.Lett., 21, 2011
7V1I	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (with an m7GMP-Arg28 adduct and in complex with SAH) 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Core protein, GLYCEROL, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7V1D	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH and GpppA) 分子名称: Core protein, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7V1C	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SIN) 分子名称: Core protein, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7V1G	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (with a GMP-Arg28 adduct and in complex with SAM) 分子名称: CITRIC ACID, Core protein, GLYCEROL, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7V1E	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH and m7GpppAmG) 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-ADENOSINE, Core protein, GLYCEROL, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022

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