1NN8
CryoEM structure of poliovirus receptor bound to poliovirus
Summary for 1NN8
Entry DOI | 10.2210/pdb1nn8/pdb |
Related | 1DGI |
Descriptor | poliovirus receptor, coat protein VP1, coat protein VP2, ... (6 entities in total) |
Functional Keywords | icosahedral virus, picornavirus, virus-receptor complex, virus/receptor |
Biological source | Homo sapiens (human) More |
Cellular location | Isoform Alpha: Cell membrane; Single-pass type I membrane protein. Isoform Delta: Cell membrane; Single-pass type I membrane protein. Isoform Beta: Secreted. Isoform Gamma: Secreted: P15151 Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03300 P03300 P03300 P03300 |
Total number of polymer chains | 7 |
Total formula weight | 196051.10 |
Authors | He, Y.,Mueller, S.,Chipman, P.R.,Bator, C.M.,Peng, X.,Bowman, V.D.,Mukhopadhyay, S.,Wimmer, E.,Kuhn, R.J.,Rossmann, M.G. (deposition date: 2003-01-13, release date: 2004-01-27, Last modification date: 2024-02-14) |
Primary citation | He, Y.,Mueller, S.,Chipman, P.R.,Bator, C.M.,Peng, X.,BOWMAN, V.D.,MUKHOPADHYAY, S.,Wimmer, E.,Kuhn, R.J.,Rossmann, M.G. Complexes of poliovirus serotypes with their common cellular receptor, CD155 J.Virol., 77:4827-4835, 2003 Cited by PubMed: 12663789DOI: 10.1128/JVI.77.8.4827-4835.2003 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (15 Å) |
Structure validation
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