1NN8

CryoEM structure of poliovirus receptor bound to poliovirus

Summary for 1NN8

Related1DGI
Descriptorpoliovirus receptor, coat protein VP1, coat protein VP2, ... (6 entities in total)
Functional Keywordsicosahedral virus, picornavirus, virus-receptor complex, virus/receptor
Biological sourceHomo sapiens (human)
More
Cellular locationIsoform Alpha: Cell membrane; Single-pass type I membrane protein. Isoform Delta: Cell membrane; Single-pass type I membrane protein. Isoform Beta: Secreted. Isoform Gamma: Secreted P15151
Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential) P03300 P03300 P03300 P03300
Total number of polymer chains7
Total molecular weight196051.1
Authors
He, Y.,Mueller, S.,Chipman, P.R.,Bator, C.M.,Peng, X.,Bowman, V.D.,Mukhopadhyay, S.,Wimmer, E.,Kuhn, R.J.,Rossmann, M.G. (deposition date: 2003-01-13, release date: 2004-01-27, Last modification date: 2011-07-13)
Primary citation
He, Y.,Mueller, S.,Chipman, P.R.,Bator, C.M.,Peng, X.,BOWMAN, V.D.,MUKHOPADHYAY, S.,Wimmer, E.,Kuhn, R.J.,Rossmann, M.G.
Complexes of poliovirus serotypes with their common cellular receptor, CD155
J.Virol., 77:4827-4835, 2003
PubMed: 12663789 (PDB entries with the same primary citation)
DOI: 10.1128/JVI.77.8.4827-4835.2003
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

Clashscore279MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

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More Biological unit images

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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (1nn8.pdb1.gz [2.01 MB])