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1VRH

HRV14/SDZ 880-061 COMPLEX

Summary for 1VRH
Entry DOI10.2210/pdb1vrh/pdb
DescriptorRHINOVIRUS 14, 2-[4-(2H-1,4-BENZOTHIAZINE-3-YL)-PIPERAZINE-1-LY]-1,3-THIAZOLE-4-CARBOXYLIC ACID ETHYLESTER, ... (5 entities in total)
Functional Keywordsrhinovirus coat protein, antiviral agents, polyprotein, coat protein, core protein, rna polymerase, hydrolase, thiol protease, myristylation, icosahedral virus, virus
Biological sourceHuman rhinovirus 14
More
Cellular locationProtein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03303 P03303 P03303 P03303
Total number of polymer chains4
Total formula weight94871.03
Authors
Oren, D.A.,Zhang, A.,Arnold, E. (deposition date: 1996-02-26, release date: 1997-02-12, Last modification date: 2023-03-15)
Primary citationOren, D.A.,Zhang, A.,Nesvadba, H.,Rosenwirth, B.,Arnold, E.
Synthesis and activity of piperazine-containing antirhinoviral agents and crystal structure of SDZ 880-061 bound to human rhinovirus 14.
J.Mol.Biol., 259:120-134, 1996
Cited by
PubMed: 8648640
DOI: 10.1006/jmbi.1996.0307
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3 Å)
Structure validation

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