2XYA
Non-covalent inhibtors of rhinovirus 3C protease.
Summary for 2XYA
Entry DOI | 10.2210/pdb2xya/pdb |
Related | 1A3R 1CQQ 1FPN 1V9U 2HRV |
Descriptor | PICORNAIN 3C, 2-PHENYLQUINOLIN-4-OL (3 entities in total) |
Functional Keywords | hydrolase, cysteine protease |
Biological source | HUMAN RHINOVIRUS SP. |
Cellular location | Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P04936 |
Total number of polymer chains | 1 |
Total formula weight | 20347.05 |
Authors | Petersen, J.,Edman, K.,Edfeldt, F.,Johansson, C. (deposition date: 2010-11-16, release date: 2011-04-27, Last modification date: 2024-05-08) |
Primary citation | Baxter, A.,Chambers, M.,Edfeldt, F.,Edman, K.,Freeman, A.,Johansson, C.,King, S.,Morley, A.,Petersen, J.,Rawlins, P.,Spadola, L.,Thong, B.,Poel, H.V.,Williams, N. Non-Covalent Inhibitors of Rhinovirus 3C Protease. Bioorg.Med.Chem.Lett., 21:777-, 2011 Cited by PubMed: 21183345DOI: 10.1016/J.BMCL.2010.11.110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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