3KOA
 
 | | M296I mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA and GTP | | 分子名称: | 3D polymerase, DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R. | | 登録日 | 2009-11-13 | | 公開日 | 2010-07-07 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin
J.Virol., 84, 2010
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3KNA
 | | M296I mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA | | 分子名称: | 3D polymerase, MAGNESIUM ION, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), ... | | 著者 | Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R. | | 登録日 | 2009-11-12 | | 公開日 | 2010-07-07 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin
J.Virol., 84, 2010
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3KLV
 | | M296I G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA | | 分子名称: | 3D polymerase, MAGNESIUM ION, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), ... | | 著者 | Ferrer-Orta, C, Sierra, M, Agudo, R, Perez-Luque, R, Arias, A, Verdaguer, N. | | 登録日 | 2009-11-09 | | 公開日 | 2010-07-07 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin
J.Virol., 84, 2010
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3KMQ
 | | G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA, tetragonal structure | | 分子名称: | 3D polymerase, RNA (5'-R(*GP*GP*CP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*CP*C)-3') | | 著者 | Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R. | | 登録日 | 2009-11-11 | | 公開日 | 2010-07-07 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin
J.Virol., 84, 2010
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3N6N
 | | crystal structure of EV71 RdRp in complex with Br-UTP | | 分子名称: | 5-bromouridine 5'-(tetrahydrogen triphosphate), NICKEL (II) ION, RNA-dependent RNA polymerase | | 著者 | Wu, Y, Lou, Z.Y, Miao, Y, Yu, Y, Rao, Z.H. | | 登録日 | 2010-05-26 | | 公開日 | 2011-06-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China.
Protein Cell, 1, 2010
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3KMS
 | | G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA trigonal structure | | 分子名称: | 3D polymerase, MAGNESIUM ION, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), ... | | 著者 | Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R. | | 登録日 | 2009-11-11 | | 公開日 | 2010-07-07 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin
J.Virol., 84, 2010
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3NAH
 | | Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase | | 分子名称: | RNA dependent RNA polymerase, SULFATE ION | | 著者 | Kim, K.H, Lee, J.H, Alam, I, Park, Y, Kang, S. | | 登録日 | 2010-06-02 | | 公開日 | 2011-06-08 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase
To be Published
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3NL0
 | | Mutant P44S M296I of Foot-and-mouth disease Virus RNA-dependent RNA polymerase | | 分子名称: | 3D polymerase, 5'-R(*G*GP*GP*CP*CP*C)-3', 5'-R(P*UP*GP*GP*GP*CP*CP*C)-3', ... | | 著者 | Agudo, R, Ferrer-Orta, C, Arias, A, Perez-Luque, R, Verdaguer, N, Domingo, E. | | 登録日 | 2010-06-21 | | 公開日 | 2011-07-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.
Plos Pathog., 6, 2010
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3NAI
 | | Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase | | 分子名称: | 5-FLUOROURACIL, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Kim, K.H, Lee, J.H, Alam, I, Park, Y, Kang, S. | | 登録日 | 2010-06-02 | | 公開日 | 2011-06-08 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase
To be Published
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3N6M
 | | Crystal structure of EV71 RdRp in complex with GTP | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, NICKEL (II) ION, RNA-dependent RNA polymerase | | 著者 | Wu, Y, Lou, Z.Y, Miao, Y, Yu, Y, Rao, Z.H. | | 登録日 | 2010-05-26 | | 公開日 | 2011-06-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China.
Protein Cell, 1, 2010
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3NKY
 | | Structure of a mutant P44S of Foot-and-mouth disease Virus RNA-dependent RNA polymerase | | 分子名称: | 3D polymerase, MAGNESIUM ION | | 著者 | Agudo, R, Ferrer-Orta, C, Arias, A, Perez-Luque, R, Verdaguer, N, Domingo, E. | | 登録日 | 2010-06-21 | | 公開日 | 2011-05-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.
Plos Pathog., 6, 2010
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3N6L
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3NMA
 | | Mutant P169S of Foot-and-mouth disease Virus RNA dependent RNA-polymerase | | 分子名称: | 5'-R(*GP*GP*C)-3', 5'-R(P*CP*C)-3', Genome polyprotein, ... | | 著者 | Agudo, R, Ferrer-Orta, C, Arias, A, Perez-Luque, R, Verdaguer, N, Domingo, E. | | 登録日 | 2010-06-22 | | 公開日 | 2011-05-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.
Plos Pathog., 6, 2010
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4LQ9
 | | Crystal structure of human norovirus RNA-dependent RNA-polymerase in complex with NAF2 | | 分子名称: | MAGNESIUM ION, RNA-dependent RNA-polymerase, naphthalene-1,5-disulfonic acid | | 著者 | Milani, M, Tarantino, D, Mastrangelo, E, Croci, R. | | 登録日 | 2013-07-17 | | 公開日 | 2014-02-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase.
Antiviral Res., 102, 2014
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4LQ3
 | | Crystal structure of human norovirus RNA-dependent RNA-polymerase bound to the inhibitor PPNDS | | 分子名称: | 3-[(E)-{4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]pyridin-2-yl}diazenyl]-7-nitronaphthalene-1,5-disulfonic acid, 5'-R(P*GP*G)-3', MAGNESIUM ION, ... | | 著者 | Milani, M, Tarantino, D, Mastrangelo, E, Croci, R. | | 登録日 | 2013-07-17 | | 公開日 | 2014-02-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase.
Antiviral Res., 102, 2014
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4NLT
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4NZ0
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4NLS
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4NYZ
 | | The EMCV 3Dpol structure with altered motif A conformation at 2.15A resolution | | 分子名称: | GLUTAMINE, GLYCEROL, Genome polyprotein, ... | | 著者 | Vives-adrian, L, Lujan, C, Ferrer-orta, C, Verdaguer, N. | | 登録日 | 2013-12-11 | | 公開日 | 2014-03-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The crystal structure of a cardiovirus RNA-dependent RNA polymerase reveals an unusual conformation of the polymerase active site
J.Virol., 88, 2014
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4NLQ
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4NLO
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4NRU
 | | Murine Norovirus RNA-dependent-RNA-polymerase in complex with Compound 6, a suramin derivative | | 分子名称: | 4-({4-methyl-3-[(3-nitrobenzoyl)amino]benzoyl}amino)naphthalene-1,5-disulfonic acid, MAGNESIUM ION, RNA dependent RNA polymerase | | 著者 | Milani, M, Croci, R, Pezzullo, M, Tarantino, D, Mastrangelo, E, Bolognesi, M. | | 登録日 | 2013-11-27 | | 公開日 | 2014-10-15 | | 最終更新日 | 2024-11-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds.
Plos One, 9, 2014
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4O4R
 | | Murine Norovirus RdRp in complex with PPNDS | | 分子名称: | 3-[(E)-{4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]pyridin-2-yl}diazenyl]-7-nitronaphthalene-1,5-disulfonic acid, RNA-dependent-RNA-polymerase, SULFATE ION | | 著者 | Croci, R, Tarantino, D, Milani, M, Pezzullo, M, Bolognesi, M, Mastrangelo, E. | | 登録日 | 2013-12-19 | | 公開日 | 2014-11-05 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | PPNDS inhibits murine Norovirus RNA-dependent RNA-polymerase mimicking two RNA stacking bases.
Febs Lett., 588, 2014
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4NLP
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4NLX
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