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3N6N

crystal structure of EV71 RdRp in complex with Br-UTP

Summary for 3N6N
Entry DOI10.2210/pdb3n6n/pdb
Related3N6L 3N6M
DescriptorRNA-dependent RNA polymerase, NICKEL (II) ION, 5-bromouridine 5'-(tetrahydrogen triphosphate), ... (4 entities in total)
Functional Keywordsev71, rdrp, br-utp, transferase
Biological sourceHuman enterovirus 71
Total number of polymer chains1
Total formula weight53167.35
Authors
Wu, Y.,Lou, Z.Y.,Miao, Y.,Yu, Y.,Rao, Z.H. (deposition date: 2010-05-26, release date: 2011-06-15, Last modification date: 2023-11-01)
Primary citationWu, Y.,Lou, Z.,Miao, Y.,Yu, Y.,Dong, H.,Peng, W.,Bartlam, M.,Li, X.,Rao, Z.
Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China.
Protein Cell, 1:491-500, 2010
Cited by
PubMed: 21203964
DOI: 10.1007/s13238-010-0061-7
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.9 Å)
Structure validation

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