PDB: 259 件ウェブページステータス検索Chemie searchBIRD

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8SZ4	Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state showing the PH domain 分子名称: Dynamin-1 著者 Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E. 登録日 2023-05-26 公開日 2024-05-01 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission. Dev.Cell, 2024
8T0R	Cryo-EM of the GDP-bound human dynamin (full-length) polymer assembled on the membrane in the super constricted state (full helix) 分子名称: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E. 登録日 2023-06-01 公開日 2024-05-01 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.97 Å) 主引用文献 Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission. Dev.Cell, 2024
4K2O	The Structure of a Triple Mutant of the Tiam1 PH-CC-Ex Domain 分子名称: T-lymphoma invasion and metastasis-inducing protein 1 著者 Joshi, M, Gakhar, L, Fuentes, E.J. 登録日 2013-04-09 公開日 2013-07-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 High-resolution structure of the Tiam1 PHn-CC-Ex domain. Acta Crystallogr.,Sect.F, 69, 2013
6TT2	The PH domain of Bruton's tyrosine kinase mutant R28C 分子名称: MAGNESIUM ION, Tyrosine-protein kinase BTK, ZINC ION 著者 Brear, P, Wagstaff, J, Hyvonen, M. 登録日 2019-12-23 公開日 2020-11-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Crystal Structure of 1-methylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C To Be Published
6TSE	Crystal Structure of 1-methylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C 分子名称: 1-methylindole-2,3-dione, MAGNESIUM ION, Tyrosine-protein kinase BTK, ... 著者 Brear, P, Wagstaff, J, Hyvonen, M. 登録日 2019-12-20 公開日 2020-11-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Crystal Structure of 1-methylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C To Be Published
6TUH	The PH domain of Bruton's tyrosine kinase mutant R28C 分子名称: 4,5,6,7-tetrahydro-1-benzofuran-3-carboxylic acid, MAGNESIUM ION, Tyrosine-protein kinase BTK, ... 著者 Brear, P, Wagstaff, J, Hyvonen, M. 登録日 2020-01-07 公開日 2020-11-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of 1-methylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C To Be Published
6U3E	Best fitting antiparallel model for Volume 1 of truncated dimeric Cytohesin-3 (Grp1; amino acids 14-399) 分子名称: Cytohesin-3, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE 著者 Das, S, Lambright, D.G. 登録日 2019-08-21 公開日 2019-09-25 最終更新日 2023-11-29 実験手法 ELECTRON MICROSCOPY (53 Å) 主引用文献 Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes. Structure, 27, 2019
6TVN	Crystal Structure of 5-bromoindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase 分子名称: 5-bromanyl-1,3-dihydroindol-2-one, MAGNESIUM ION, Tyrosine-protein kinase BTK, ... 著者 Brear, P, Wagstaff, J, Hyvonen, M. 登録日 2020-01-10 公開日 2020-11-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Crystal Structure of 1-methylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C To Be Published
6D8Z	Crystal Structure of the C-terminal Guanine Nucleotide Exchange Factor Module of Human Trio 分子名称: Triple functional domain protein 著者 Bandekar, S, Tesmer, J.J. 登録日 2018-04-27 公開日 2019-02-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure of the C-terminal guanine nucleotide exchange factor module of Trio in an autoinhibited conformation reveals its oncogenic potential. Sci Signal, 12, 2019
6DLU	Cryo-EM of the GMPPCP-bound human dynamin-1 polymer assembled on the membrane in the constricted state 分子名称: Dynamin-1, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER 著者 Kong, L, Wang, H, Fang, S, Canagarajah, B, Kehr, A.D, Rice, W.J, Hinshaw, J.E. 登録日 2018-06-02 公開日 2018-08-01 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.75 Å) 主引用文献 Cryo-EM of the dynamin polymer assembled on lipid membrane. Nature, 560, 2018
4MT6	Crystal structure of closed inactive collybistin 分子名称: Rho guanine nucleotide exchange factor 9 著者 Schneeberger, D, Schindelin, H. 登録日 2013-09-19 公開日 2014-08-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (5.501 Å) 主引用文献 A conformational switch in collybistin determines the differentiation of inhibitory postsynapses. Embo J., 33, 2014
3SNH	Crystal structure of nucleotide-free human dynamin1 分子名称: Dynamin-1 著者 Faelber, K, Daumke, O. 登録日 2011-06-29 公開日 2011-09-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Crystal structure of nucleotide-free dynamin. Nature, 477, 2011
3TCA	Crystal structure of the Ras-associating and pleckstrin-homology domains of RIAM 分子名称: Amyloid beta A4 precursor protein-binding family B member 1-interacting protein 著者 Wu, J, Hubbard, S.R. 登録日 2011-08-08 公開日 2012-09-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Rap1-interacting adapter molecule (RIAM) associates with the plasma membrane via a proximity detector. J.Cell Biol., 199, 2012
1XDV	Experimentally Phased Structure of Human the Son of Sevenless protein at 4.1 Ang. 分子名称: Son of sevenless protein homolog 1 著者 Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J. 登録日 2004-09-08 公開日 2004-11-02 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (4.1 Å) 主引用文献 Structural analysis of autoinhibition in the ras activator son of sevenless. Cell(Cambridge,Mass.), 119, 2004
1BWN	PH DOMAIN AND BTK MOTIF FROM BRUTON'S TYROSINE KINASE MUTANT E41K IN COMPLEX WITH INS(1,3,4,5)P4 分子名称: BRUTON'S TYROSINE KINASE, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, ZINC ION 著者 Djinovic Carugo, K, Baraldi, E, Hyvoenen, M, Lo Surdo, P, Riley, A, Potter, B, Saraste, M. 登録日 1998-09-25 公開日 1999-06-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate. Structure Fold.Des., 7, 1999
1B55	PH DOMAIN FROM BRUTON'S TYROSINE KINASE IN COMPLEX WITH INOSITOL 1,3,4,5-TETRAKISPHOSPHATE 分子名称: INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, TYROSINE-PROTEIN KINASE BTK, ZINC ION 著者 Djinovic Carugo, K, Baraldi, E, Hyvoenen, M, Lo Surdo, P, Riley, A.M, Potter, B.V.L, O'Brien, R, Ladbury, J.E, Saraste, M. 登録日 1999-01-12 公開日 1999-06-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate. Structure Fold.Des., 7, 1999
1XD4	Crystal structure of the DH-PH-cat module of Son of Sevenless (SOS) 分子名称: Son of sevenless protein homolog 1 著者 Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J. 登録日 2004-09-03 公開日 2004-11-02 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.64 Å) 主引用文献 Structural analysis of autoinhibition in the ras activator son of sevenless. Cell(Cambridge,Mass.), 119, 2004
1BTK	PH DOMAIN AND BTK MOTIF FROM BRUTON'S TYROSINE KINASE MUTANT R28C 分子名称: BRUTON'S TYROSINE KINASE, SODIUM ION, ZINC ION 著者 Hyvonen, M, Saraste, M. 登録日 1997-07-01 公開日 1997-09-17 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of the PH domain and Btk motif from Bruton's tyrosine kinase: molecular explanations for X-linked agammaglobulinaemia. EMBO J., 16, 1997
1DBH	DBL AND PLECKSTRIN HOMOLOGY DOMAINS FROM HSOS1 分子名称: PROTEIN (HUMAN SOS 1) 著者 Soisson, S.M, Kuriyan, J. 登録日 1998-12-17 公開日 1998-12-23 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein. Cell(Cambridge,Mass.), 95, 1998
3ZVR	Crystal structure of Dynamin 分子名称: DYNAMIN-1, PENTAETHYLENE GLYCOL 著者 Ford, M.G.J, Jenni, S, Nunnari, J. 登録日 2011-07-27 公開日 2011-09-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The Crystal Structure of Dynamin Nature, 477, 2011
3ZYS	Human dynamin 1 deltaPRD polymer stabilized with GMPPCP 分子名称: DYNAMIN-1, INTERFERON-INDUCED GTP-BINDING PROTEIN MX1 著者 Chappie, J.S, Mears, J.A, Fang, S, Leonard, M, Schmid, S.L, Milligan, R.A, Hinshaw, J.E, Dyda, F. 登録日 2011-08-24 公開日 2011-10-12 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (12.2 Å) 主引用文献 A Pseudoatomic Model of the Dynamin Polymer Identifies a Hydrolysis-Dependent Powerstroke. Cell(Cambridge,Mass.), 147, 2011
2LKO	Structural Basis of Phosphoinositide Binding to Kindlin-2 Pleckstrin Homology Domain in Regulating Integrin Activation 分子名称: Fermitin family homolog 2, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE 著者 Liu, J, Fukuda, K, Xu, Z. 登録日 2011-10-17 公開日 2011-10-26 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural basis of phosphoinositide binding to kindlin-2 protein pleckstrin homology domain in regulating integrin activation. J.Biol.Chem., 286, 2011
2LUL	Solution NMR Structure of PH Domain of Tyrosine-protein kinase Tec from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR3504C 分子名称: Tyrosine-protein kinase Tec, ZINC ION 著者 Liu, G, Xiao, R, Janjua, H, Hamilton, K, Shastry, R, Kohan, E, Acton, T.B, Everett, J.K, Lee, H, Pederson, K, Huang, Y.J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2012-06-15 公開日 2012-08-15 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution NMR Structure of PH Domain of Tyrosine-protein kinase Tec from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR3504C To be Published
2Q13	Crystal structure of BAR-PH domain of APPL1 分子名称: DCC-interacting protein 13 alpha 著者 Zhu, G, Zhang, X.C. 登録日 2007-05-23 公開日 2007-08-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5. Embo J., 26, 2007
2Z0P	Crystal structure of PH domain of Bruton's tyrosine kinase 分子名称: (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE, Tyrosine-protein kinase BTK, ZINC ION 著者 Murayama, K, Kato-Murayama, M, Mishima, C, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-05-07 公開日 2008-05-13 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Crystal structure of the Bruton's tyrosine kinase PH domain with phosphatidylinositol Biochem.Biophys.Res.Commun., 377, 2008

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