4GN1

Crystal Structure of the RA and PH domains of Lamellipodin

Summary for 4GN1

Entry DOI	10.2210/pdb4gn1/pdb
Related	4GMV
Descriptor	Ras-associated and pleckstrin homology domains-containing protein 1, MALONATE ION (3 entities in total)
Functional Keywords	ra-ph, coiled-coil region, ras-association domain, pleckstrin homology domain, cytoskeletal protein, ena/vasp binding, cell migration, cell adhesion, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Peripheral membrane protein; Cytoplasmic side: Q70E73
Total number of polymer chains	4
Total formula weight	121420.04
Authors	Chang, Y.C.E.,Wu, J. (deposition date: 2012-08-16, release date: 2012-11-28, Last modification date: 2023-09-13)
Primary citation	Chang, Y.C.,Zhang, H.,Brennan, M.L.,Wu, J. Crystal structure of Lamellipodin implicates diverse functions in actin polymerization and Ras signaling. Protein Cell, 4:211-219, 2013 Cited by PubMed: 23483482 DOI: 10.1007/s13238-013-2082-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation