4GMV
Crystal Structure of the coiled-coil, RA and PH domains of Lamellipodin
Summary for 4GMV
| Entry DOI | 10.2210/pdb4gmv/pdb |
| Related | 4GN1 |
| Descriptor | Ras-associated and pleckstrin homology domains-containing protein 1 (2 entities in total) |
| Functional Keywords | ra-ph, coiled-coil region, ras-association domain, pleckstrin homology domain, cytoskeletal protein, ena/vasp binding, cell migration, cell adhesion |
| Biological source | Homo sapiens (human) |
| Cellular location | Cell membrane; Peripheral membrane protein; Cytoplasmic side: Q70E73 |
| Total number of polymer chains | 2 |
| Total formula weight | 66468.84 |
| Authors | Chang, Y.C.E.,Wu, J. (deposition date: 2012-08-16, release date: 2012-11-28, Last modification date: 2023-09-13) |
| Primary citation | Chang, Y.C.,Zhang, H.,Brennan, M.L.,Wu, J. Crystal structure of Lamellipodin implicates diverse functions in actin polymerization and Ras signaling. Protein Cell, 4:211-219, 2013 Cited by PubMed: 23483482DOI: 10.1007/s13238-013-2082-5 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.403 Å) |
Structure validation
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