4H6Y

Crystal structure of the DH-PH-PH domain of FARP1

Summary for 4H6Y

• Entry DOI: 10.2210/pdb4h6y/pdb
• Related: 4GZU
• Descriptor: FERM, RhoGEF and pleckstrin domain-containing protein 1 (1 entity in total)
• Functional Keywords: farp1, dh-ph, gef, guanine nucleotide exchange factor, signaling protein
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Peripheral membrane protein; Cytoplasmic side: Q9Y4F1
• Total number of polymer chains: 2
• Total formula weight: 115839.84

Authors

He, X.,Zhang, X. (deposition date: 2012-09-19, release date: 2013-03-13, Last modification date: 2024-02-28)

• Primary citation: He, X.,Kuo, Y.C.,Rosche, T.J.,Zhang, X.; Structural Basis for Autoinhibition of the Guanine Nucleotide Exchange Factor FARP2.; Structure, 21:355-364, 2013; PubMed: 23375260; DOI: 10.1016/j.str.2013.01.001

Experimental method

X-RAY DIFFRACTION (4.09 Å)