4H8S

Crystal structure of human APPL2BARPH domain

Summary for 4H8S

Entry DOI	10.2210/pdb4h8s/pdb
Related	2ELB 2Q12 2Q13 2Z0N 2Z0O
Descriptor	DCC-interacting protein 13-beta (1 entity in total)
Functional Keywords	bar domain, pleckstrin homology domain, adaptor protein, rab binding, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Early endosome membrane; Peripheral membrane protein: Q8NEU8
Total number of polymer chains	4
Total formula weight	184484.88
Authors	Martin, J.L.,King, G.J. (deposition date: 2012-09-23, release date: 2012-10-17, Last modification date: 2023-09-20)
Primary citation	King, G.J.,Stockli, J.,Hu, S.H.,Winnen, B.,Duprez, W.G.,Meoli, C.C.,Junutula, J.R.,Jarrott, R.J.,James, D.E.,Whitten, A.E.,Martin, J.L. Membrane Curvature Protein Exhibits Interdomain Flexibility and Binds a Small GTPase. J.Biol.Chem., 287:40996-41006, 2012 Cited by PubMed: 23055524 DOI: 10.1074/jbc.M112.349803 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation