6MOJ
| Dimeric DARPin A_angle_R5 complex with EpoR | 分子名称: | D(-)-TARTARIC ACID, Dimeric DARPin ACR5 (A_angle_R5), Erythropoietin receptor, ... | 著者 | Jude, K.M, Mohan, K, Garcia, K.C. | 登録日 | 2018-10-04 | 公開日 | 2019-06-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.431 Å) | 主引用文献 | Topological control of cytokine receptor signaling induces differential effects in hematopoiesis. Science, 364, 2019
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6MOK
| Dimeric DARPin A_distance_R7 complex with EpoR | 分子名称: | Dimeric DARPin ANR7 (A_distance_r7), Erythropoietin receptor | 著者 | Jude, K.M, Mohan, K, Garcia, K.C, Guo, Y. | 登録日 | 2018-10-04 | 公開日 | 2019-06-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (5.101 Å) | 主引用文献 | Topological control of cytokine receptor signaling induces differential effects in hematopoiesis. Science, 364, 2019
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6HN4
| Leucine-zippered human insulin receptor ectodomain with single bound insulin - "lower" membrane-proximal part | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor,Insulin receptor,General control protein GCN4 | 著者 | Weis, F, Menting, J.G, Margetts, M.B, Chan, S.J, Xu, Y, Tennagels, N, Wohlfart, P, Langer, T, Mueller, C.W, Dreyer, M.K, Lawrence, M.C. | 登録日 | 2018-09-14 | 公開日 | 2018-11-21 | 最終更新日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | The signalling conformation of the insulin receptor ectodomain. Nat Commun, 9, 2018
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6HNF
| Structure in solution of human fibronectin type III-domain 14 | 分子名称: | Fibronectin | 著者 | Zhong, X, Arnolds, O, Krenczyk, O, Gajewski, J, Puetz, S, Herrmann, C, Stoll, R. | 登録日 | 2018-09-14 | 公開日 | 2018-10-10 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | The Structure in Solution of Fibronectin Type III Domain 14 Reveals Its Synergistic Heparin Binding Site. Biochemistry, 57, 2018
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6HN5
| Leucine-zippered human insulin receptor ectodomain with single bound insulin - "upper" membrane-distal part | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin, ... | 著者 | Weis, F, Menting, J.G, Margetts, M.B, Chan, S.J, Xu, Y, Tennagels, N, Wohlfart, P, Langer, T, Mueller, C.W, Dreyer, M.K, Lawrence, M.C. | 登録日 | 2018-09-14 | 公開日 | 2018-11-21 | 最終更新日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The signalling conformation of the insulin receptor ectodomain. Nat Commun, 9, 2018
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6MFA
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6GVL
| Second pair of Fibronectin type III domains of integrin beta4 bound to the bullous pemphigoid antigen BP230 (BPAG1e) | 分子名称: | Dystonin, Integrin beta-4 | 著者 | Manso, J.A, Gomez-Hernandez, M, Alonso-Garcia, N, de Pereda, J.M. | 登録日 | 2018-06-21 | 公開日 | 2019-03-20 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Integrin alpha 6 beta 4 Recognition of a Linear Motif of Bullous Pemphigoid Antigen BP230 Controls Its Recruitment to Hemidesmosomes. Structure, 27, 2019
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6GVK
| Second pair of Fibronectin type III domains of integrin beta4 (T1663R mutant) bound to the bullous pemphigoid antigen BP230 (BPAG1e) | 分子名称: | Dystonin, GLYCEROL, Integrin beta-4 | 著者 | Manso, J.A, Gomez-Hernandez, M, Alonso-Garcia, N, de Pereda, J.M. | 登録日 | 2018-06-21 | 公開日 | 2019-03-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Integrin alpha 6 beta 4 Recognition of a Linear Motif of Bullous Pemphigoid Antigen BP230 Controls Its Recruitment to Hemidesmosomes. Structure, 27, 2019
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6CE9
| Insulin Receptor ectodomain in complex with two insulin molecules | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B. | 登録日 | 2018-02-11 | 公開日 | 2018-03-14 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis. Nature, 556, 2018
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6CEB
| Insulin Receptor ectodomain in complex with two insulin molecules - C1 symmetry | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B. | 登録日 | 2018-02-11 | 公開日 | 2018-03-14 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis. Nature, 556, 2018
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6CE7
| Insulin Receptor ectodomain in complex with one insulin molecule | 分子名称: | Insulin A chain, Insulin B chain, Insulin receptor, ... | 著者 | Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B. | 登録日 | 2018-02-11 | 公開日 | 2018-03-14 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (7.4 Å) | 主引用文献 | Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis. Nature, 556, 2018
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6BRB
| Novel non-antibody protein scaffold targeting CD40L | 分子名称: | CD40 ligand, Tn3-like, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Oganesyan, V, Baca, M, Thisted, T, Grinberg, L, Wu, H, Dall'Acqua, W.F. | 登録日 | 2017-11-30 | 公開日 | 2018-12-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | 主引用文献 | A CD40L-targeting protein reduces autoantibodies and improves disease activity in patients with autoimmunity. Sci Transl Med, 11, 2019
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5XWT
| Crystal structure of PTPdelta Ig1-Fn1 in complex with SALM5 LRR-Ig | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Goto-Ito, S, Yamagata, A, Sato, Y, Fukai, S. | 登録日 | 2017-06-30 | 公開日 | 2018-06-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (4.178 Å) | 主引用文献 | Structural basis of trans-synaptic interactions between PTP delta and SALMs for inducing synapse formation. Nat Commun, 9, 2018
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5X83
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5UTK
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5N48
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5N47
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5N06
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5MYB
| Homodimerization of Tie2 Fibronectin-like domains 2 and 3 in space group P21 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiopoietin-1 receptor, ... | 著者 | Leppanen, V.-M, Saharinen, P, Alitalo, K. | 登録日 | 2017-01-26 | 公開日 | 2017-04-26 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5MYA
| Homodimerization of Tie2 Fibronectin-like domains 1-3 in space group C2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiopoietin-1 receptor, ... | 著者 | Leppanen, V.-M, Saharinen, P, Alitalo, K. | 登録日 | 2017-01-26 | 公開日 | 2017-04-26 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5U8R
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5U8Q
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5M0A
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5LKN
| NMR solution structure of human FNIII domain 2 of NCAM | 分子名称: | Neural cell adhesion molecule 1 | 著者 | Slapsak, U, Salzano, G, Amin, L, Abskharon, R.N.N, Ilc, G, Zupancic, B, Biljan, I, Plavec, J, Giachin, G, Legname, G. | 登録日 | 2016-07-22 | 公開日 | 2016-09-14 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | The N Terminus of the Prion Protein Mediates Functional Interactions with the Neuronal Cell Adhesion Molecule (NCAM) Fibronectin Domain. J.Biol.Chem., 291, 2016
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5KF4
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