6MOF

Monomeric DARPin G2 complex with EpoR

Summary for 6MOF

• Entry DOI: 10.2210/pdb6mof/pdb
• Related: 6MOE
• Descriptor: G2 DARPin, Erythropoietin receptor, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: complex, receptor, darpin, biosynthetic protein
• Biological source: synthetic construct; More
• Total number of polymer chains: 2
• Total formula weight: 42937.66

Authors

Jude, K.M.,Mohan, K.,Garcia, K.C. (deposition date: 2018-10-04, release date: 2019-06-05, Last modification date: 2023-10-11)

• Primary citation: Mohan, K.,Ueda, G.,Kim, A.R.,Jude, K.M.,Fallas, J.A.,Guo, Y.,Hafer, M.,Miao, Y.,Saxton, R.A.,Piehler, J.,Sankaran, V.G.,Baker, D.,Garcia, K.C.; Topological control of cytokine receptor signaling induces differential effects in hematopoiesis.; Science, 364:-, 2019; PubMed: 31123111; DOI: 10.1126/science.aav7532

Experimental method

X-RAY DIFFRACTION (2.894 Å)