6MHO
 
 | | Structure of the human TRPV3 channel in the apo conformation | | 分子名称: | Transient receptor potential cation channel subfamily V member 3 | | 著者 | Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y. | | 登録日 | 2018-09-18 | | 公開日 | 2018-10-03 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Conformational ensemble of the human TRPV3 ion channel.
Nat Commun, 9, 2018
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6O20
 | | Cryo-EM structure of TRPV5 with calmodulin bound | | 分子名称: | CALCIUM ION, Calmodulin, Transient receptor potential cation channel subfamily V member 5 | | 著者 | Dang, S, van Goor, M.K, Asarnow, D, Wang, Y, Julius, D, Cheng, Y, van der Wijst, J. | | 登録日 | 2019-02-22 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural insight into TRPV5 channel function and modulation.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6O1N
 | | Cryo-EM structure of TRPV5 (1-660) in nanodisc | | 分子名称: | Transient receptor potential cation channel subfamily V member 5 | | 著者 | Dang, S, van Goor, M.K, Asarnow, D, Wang, Y, Julius, D, Cheng, Y, van der Wijst, J. | | 登録日 | 2019-02-21 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural insight into TRPV5 channel function and modulation.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6O1U
 | | Cryo-EM structure of TRPV5 W583A in nanodisc | | 分子名称: | Transient receptor potential cation channel subfamily V member 5 | | 著者 | Dang, S, van Goor, M.K, Asarnow, D, Wang, Y, Julius, D, Cheng, Y, van der Wijst, J. | | 登録日 | 2019-02-21 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural insight into TRPV5 channel function and modulation.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6O1P
 | | Cryo-EM structure of full length TRPV5 in nanodisc | | 分子名称: | Transient receptor potential cation channel subfamily V member 5 | | 著者 | Dang, S, van Goor, M.K, Asarnow, D, Wang, Y, Julius, D, Cheng, Y, van der Wijst, J. | | 登録日 | 2019-02-21 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural insight into TRPV5 channel function and modulation.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6AEI
 | | Cryo-EM structure of the receptor-activated TRPC5 ion channel | | 分子名称: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ... | | 著者 | Duan, J, Li, Z, Li, J, Zhang, J. | | 登録日 | 2018-08-05 | | 公開日 | 2019-08-07 | | 最終更新日 | 2019-08-14 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Cryo-EM structure of TRPC5 at 2.8- angstrom resolution reveals unique and conserved structural elements essential for channel function.
Sci Adv, 5, 2019
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6B5V
 | | Structure of TRPV5 in complex with econazole | | 分子名称: | 1-[(2R)-2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, CALCIUM ION, Transient receptor potential cation channel subfamily V member 5 | | 著者 | Hughes, T.E.T, Lodowski, D.T, Huynh, K.W, Yazici, A, del Rosario, J, Kapoor, A, Basak, S, Samanta, A, Chakrapani, S, Zhou, Z.H, Filizola, M, Rohacs, T, Han, S, Moiseenkova-Bell, V.Y. | | 登録日 | 2017-09-29 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
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6BO8
 | | Cryo-EM structure of human TRPV6 in nanodiscs | | 分子名称: | Transient receptor potential cation channel subfamily V member 6 | | 著者 | McGoldrick, L.L, Singh, A.K, Saotome, K, Yelshanskaya, M.V, Twomey, E.C, Grassucci, R.A, Sobolevsky, A.I. | | 登録日 | 2017-11-18 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Opening of the human epithelial calcium channel TRPV6.
Nature, 553, 2018
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6BO9
 | | Cryo-EM structure of human TRPV6 in amphipols | | 分子名称: | Transient receptor potential cation channel subfamily V member 6 | | 著者 | McGoldrick, L.L, Singh, A.K, Saotome, K, Yelshanskaya, M.V, Twomey, E.C, Grassucci, R.A, Sobolevsky, A.I. | | 登録日 | 2017-11-18 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Opening of the human epithelial calcium channel TRPV6.
Nature, 553, 2018
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6BOA
 | | Cryo-EM structure of human TRPV6-R470E in amphipols | | 分子名称: | Transient receptor potential cation channel subfamily V member 6 | | 著者 | McGoldrick, L.L, Singh, A.K, Saotome, K, Yelshanskaya, M.V, Twomey, E.C, Grassucci, R.A, Sobolevsky, A.I. | | 登録日 | 2017-11-18 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Opening of the human epithelial calcium channel TRPV6.
Nature, 553, 2018
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6D7S
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6DMR
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6DVZ
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6D7T
 | | Cryo-EM structure of human TRPV6-Y467A in complex with 2-Aminoethoxydiphenyl borate (2-APB) | | 分子名称: | 2-aminoethyl diphenylborinate, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6 | | 著者 | Singh, A.K, Saotome, K, McGoldrick, L.L, Sobolevsky, A.I. | | 登録日 | 2018-04-25 | | 公開日 | 2018-07-18 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (4.44 Å) | | 主引用文献 | Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB.
Nat Commun, 9, 2018
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6DMU
 | | PI(4,5)P2 bound full-length rbTRPV5 | | 分子名称: | Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | | 著者 | Hughes, T.E.T, Pumroy, R.A, Moiseenkova-Bell, V.Y. | | 登録日 | 2018-06-05 | | 公開日 | 2018-10-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural insights on TRPV5 gating by endogenous modulators.
Nat Commun, 9, 2018
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6DVY
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6DMW
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6DVW
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6E2F
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6EMK
 | | Cryo-EM Structure of Saccharomyces cerevisiae Target of Rapamycin Complex 2 | | 分子名称: | Serine/threonine-protein kinase TOR2, Target of rapamycin complex 2 subunit AVO1, Target of rapamycin complex 2 subunit AVO2, ... | | 著者 | Karuppasamy, M, Kusmider, B, Oliveira, T.M, Gaubitz, C, Prouteau, M, Loewith, R, Schaffitzel, C. | | 登録日 | 2017-10-02 | | 公開日 | 2017-12-06 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | | 主引用文献 | Cryo-EM structure of Saccharomyces cerevisiae target of rapamycin complex 2.
Nat Commun, 8, 2017
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8FOA
 | | Cryo-EM structure of human TRPV6 in complex with the natural phytoestrogen genistein | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Neuberger, A, Yelshanskaya, M.V, Nadezhdin, K.D, Sobolevsky, A.I. | | 登録日 | 2022-12-30 | | 公開日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | | 主引用文献 | Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein.
Nat Commun, 14, 2023
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8FOB
 | | Cryo-EM structure of human TRPV6 in the open state | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, ... | | 著者 | Neuberger, A, Yelshanskaya, M.V, Nadezhdin, K.D, Sobolevsky, A.I. | | 登録日 | 2022-12-30 | | 公開日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | | 主引用文献 | Structural mechanism of human oncochannel TRPV6 inhibition by the natural phytoestrogen genistein.
Nat Commun, 14, 2023
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8FFO
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8FHH
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8FHI
 | | Wildtype rabbit TRPV5 in nanodiscs in complex with oleoyl coenzyme A, Open stated | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ERGOSTEROL, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name), ... | | 著者 | De Jesus-Perez, J.J, Moiseenkova-Bell, V.Y. | | 登録日 | 2022-12-14 | | 公開日 | 2023-11-01 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A.
Nat Commun, 14, 2023
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