6URQ

Complex structure of human poly-ADP-ribosyltransferase TNKS1 ARC2-ARC3 and P antigen family member 4 (PAGE4)

Summary for 6URQ

Entry DOI	10.2210/pdb6urq/pdb
Descriptor	Poly [ADP-ribose] polymerase tankyrase-1, P antigen family member 4, SULFATE ION, ... (5 entities in total)
Functional Keywords	tnks, page4, tankyrase, parp, cancer-testis antigen, wnt signaling, transferase-transcription complex, transferase/transcription
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	92424.50
Authors	Zheng, Y.,Koirala, S.,Miller, D.,Potts, P.R. (deposition date: 2019-10-24, release date: 2020-07-29, Last modification date: 2023-10-11)
Primary citation	Koirala, S.,Klein, J.,Zheng, Y.,Glenn, N.O.,Eisemann, T.,Fon Tacer, K.,Miller, D.J.,Kulak, O.,Lu, M.,Finkelstein, D.B.,Neale, G.,Tillman, H.,Vogel, P.,Strand, D.W.,Lum, L.,Brautigam, C.A.,Pascal, J.M.,Clements, W.K.,Potts, P.R. Tissue-Specific Regulation of the Wnt/ beta-Catenin Pathway by PAGE4 Inhibition of Tankyrase. Cell Rep, 32:107922-107922, 2020 Cited by PubMed: 32698014 DOI: 10.1016/j.celrep.2020.107922 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation