8GKA

Human TRPV3 tetramer structure, closed conformation

Summary for 8GKA

Entry DOI	10.2210/pdb8gka/pdb
EMDB information	40181
Descriptor	Transient receptor potential cation channel subfamily V member 3, SODIUM ION, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (3 entities in total)
Functional Keywords	ion channel, trp channel, closed conformation, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	388076.75
Authors	Lansky, S.,Betancourt, J.M.,Scheuring, S. (deposition date: 2023-03-17, release date: 2023-09-06, Last modification date: 2023-09-20)
Primary citation	Lansky, S.,Betancourt, J.M.,Zhang, J.,Jiang, Y.,Kim, E.D.,Paknejad, N.,Nimigean, C.M.,Yuan, P.,Scheuring, S. A pentameric TRPV3 channel with a dilated pore. Nature, 621:206-214, 2023 Cited by PubMed: 37648856 DOI: 10.1038/s41586-023-06470-1 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.55 Å)

Structure validation