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8FHH

Wildtype rabbit TRPV5 in nanodiscs in the presence of oleoyl coenzyme A, Closed stated

Summary for 8FHH
Entry DOI10.2210/pdb8fhh/pdb
EMDB information29085
DescriptorTransient receptor potential cation channel subfamily V member 5, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ERGOSTEROL (3 entities in total)
Functional Keywordstrpv5, trp channel, oleoyl coenzyme a, closed state, membrane protein
Biological sourceOryctolagus cuniculus (rabbit)
Total number of polymer chains4
Total formula weight341351.83
Authors
De Jesus-Perez, J.J.,Moiseenkova-Bell, V.Y. (deposition date: 2022-12-14, release date: 2023-11-01)
Primary citationLee, B.H.,De Jesus Perez, J.J.,Moiseenkova-Bell, V.,Rohacs, T.
Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A.
Nat Commun, 14:5883-5883, 2023
Cited by
PubMed: 37735536
DOI: 10.1038/s41467-023-41577-z
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.09 Å)
Structure validation

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