PDB: 66910 件ウェブページステータス検索Chemie searchBIRD

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4MYQ	Selective Inhibition of the Catalytic Domain Of Human Phosphodiesterase 4B With A-33 分子名称: (4-{[2-(5-chlorothiophen-2-yl)-5-ethyl-6-methylpyrimidin-4-yl]amino}phenyl)acetic acid, 1,2-ETHANEDIOL, MAGNESIUM ION, ... 著者 Fox III, D, Edwards, T.E. 登録日 2013-09-27 公開日 2014-01-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for the design of selective phosphodiesterase 4B inhibitors. Cell Signal, 26, 2014
5MT2	Glycoside hydrolase BT_0996 分子名称: Beta-galactosidase, GLYCEROL 著者 Basle, A, Ndeh, D, Rogowski, A, Cartmell, A, Luis, A.S, Venditto, I, Labourel, A, Gilbert, H.J. 登録日 2017-01-06 公開日 2017-03-22 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Complex pectin metabolism by gut bacteria reveals novel catalytic functions. Nature, 544, 2017
4MXF	X-ray structure of the adduct between bovine pancreatic ribonuclease and Auoxo6, a dinuclear gold(III) complex with -dioxo bridges linking the two metal centers 分子名称: GOLD ION, Ribonuclease pancreatic 著者 Russo Krauss, I, Vergara, A, Merlino, A. 登録日 2013-09-26 公開日 2013-12-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Interactions of gold-based drugs with proteins: crystal structure of the adduct formed between ribonuclease A and a cytotoxic gold(iii) compound. Metallomics, 6, 2014
4MY2	Crystal Structure of Norrin in fusion with Maltose Binding Protein 分子名称: Maltose-binding periplasmic protein, Norrin fusion protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Ke, J, Jurecky, C, Chen, C, Gu, X, Parker, N, Williams, B.O, Melcher, K, Xu, H.E. 登録日 2013-09-27 公開日 2013-11-13 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure and function of Norrin in assembly and activation of a Frizzled 4-Lrp5/6 complex. Genes Dev., 27, 2013
4N0J	Crystal structure of dimethyllysine hen egg-white lysozyme in complex with sclx4 at 1.9 A resolution 分子名称: 25,26,27,28-tetrahydroxypentacyclo[19.3.1.1~3,7~.1~9,13~.1~15,19~]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-5,11,17,23-tetrasulfonic acid, CHLORIDE ION, GLYCEROL, ... 著者 McGovern, R.E, Crowley, P.B. 登録日 2013-10-02 公開日 2014-11-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural study of a small molecule receptor bound to dimethyllysine in lysozyme. Chem Sci, 6, 2015
6JG6	Crystal structure of barley exohydrolaseI W286A mutant in complex with methyl 6-thio-beta-gentiobioside 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1, GLYCEROL, ... 著者 Luang, S, Streltsov, V.A, Hrmova, M. 登録日 2019-02-13 公開日 2020-08-19 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases. Nat Commun, 13, 2022
4MYZ	Structure of a class 2 docking domain complex from modules CurK and CurL of the curacin A polyketide synthase 分子名称: CurK, CurL fusion protein 著者 Whicher, J.R, Smaga, S.S, Smith, J.L. 登録日 2013-09-28 公開日 2014-01-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Cyanobacterial polyketide synthase docking domains: a tool for engineering natural product biosynthesis. Chem.Biol., 20, 2013
5MUJ	BT0996 RGII Chain B Complex 分子名称: ACETATE ION, Beta-galactosidase, alpha-L-rhamnopyranose-(1-2)-[alpha-L-rhamnopyranose-(1-3)]alpha-L-arabinopyranose-(1-4)-[4-O-[(1R)-1-hydroxyethyl]-2-O-methyl-alpha-L-fucopyranose-(1-2)]beta-D-galactopyranose-(1-2)-alpha-D-aceric acid-(1-4)-alpha-L-rhamnopyranose-(1-3)-3-C-(hydroxylmethyl)-alpha-D-erythrofuranose 著者 Cartmell, A, Basle, A, Ndeh, D, Luis, A.S, Venditto, I, Labourel, A, Rogowski, A, Gilbert, H.J. 登録日 2017-01-13 公開日 2017-04-05 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Complex pectin metabolism by gut bacteria reveals novel catalytic functions. Nature, 544, 2017
6JGT	Crystal structure of barley exohydrolaseI W434Y mutant in complex with methyl 6-thio-beta-gentiobioside. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1, ... 著者 Luang, S, Streltsov, V.A, Hrmova, M. 登録日 2019-02-14 公開日 2020-08-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases. Nat Commun, 13, 2022
4N1U	Structure of human MTH1 in complex with TH588 分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, N~4~-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine, SULFATE ION 著者 Berntsson, R.P.-A, Jemth, A, Gustafsson, R, Svensson, L.M, Helleday, T, Stenmark, P. 登録日 2013-10-04 公開日 2014-04-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool. Nature, 508, 2014
6JHW	Structure of anti-CRISPR AcrIIC3 and NmeCas9 HNH 分子名称: AcrIIC3, CRISPR-associated endonuclease Cas9 著者 Suh, J.Y, Lee, B.J, Lee, S.J, Kim, Y. 登録日 2019-02-19 公開日 2019-08-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Anti-CRISPR AcrIIC3 discriminates between Cas9 orthologs via targeting the variable surface of the HNH nuclease domain. Febs J., 286, 2019
4N2Z	Crystal Structure of the alpha-L-arabinofuranosidase PaAbf62A from Podospora anserina in complex with cellotriose 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Siguier, B, Dumon, C, Mourey, L, Tranier, S. 登録日 2013-10-06 公開日 2014-01-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 First Structural Insights into alpha-L-Arabinofuranosidases from the Two GH62 Glycoside Hydrolase Subfamilies. J.Biol.Chem., 289, 2014
4N2X	Crystal Structure of DL-2-haloacid dehalogenase 分子名称: DL-2-haloacid dehalogenase, GLYCEROL 著者 Siwek, A, Omi, R, Hirotsu, K, Jitsumori, K, Esaki, N, Kurihara, T, Paneth, P. 登録日 2013-10-06 公開日 2013-11-27 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Binding modes of DL-2-haloacid dehalogenase revealed by crystallography, modeling and isotope effects studies. Arch.Biochem.Biophys., 540, 2013
4N4J	Kuenenia stuttgartiensis hydroxylamine oxidoreductase 分子名称: 1-[(4-cyclohexylbutanoyl)(2-hydroxyethyl)amino]-1-deoxy-D-glucitol, HEME C, PHOSPHATE ION, ... 著者 Maalcke, W.J, Dietl, A, Marritt, S.J, Butt, J.N, Jetten, M.S.M, Keltjens, J.T, Barends, T.R.M.B, Kartal, B. 登録日 2013-10-08 公開日 2013-12-11 最終更新日 2020-03-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis of Biological NO Generation by Octaheme Oxidoreductases. J.Biol.Chem., 289, 2014
4N4S	A Double Mutant Rat Erk2 in Complex With a Pyrazolo[3,4-d]pyrimidine Inhibitor 分子名称: 3-[2-(benzyloxy)-8-methylquinolin-6-yl]-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Mitogen-activated protein kinase 1 著者 Hari, S.B, Maly, D.J, Merritt, E.A. 登録日 2013-10-08 公開日 2014-04-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Conformation-Selective ATP-Competitive Inhibitors Control Regulatory Interactions and Noncatalytic Functions of Mitogen-Activated Protein Kinases. Chem.Biol., 21, 2014
4N7G	Crystal structure of 14-3-3zeta in complex with a peptide derived from ExoS 分子名称: 14-3-3 protein zeta/delta, Exoenzyme S, HEXAETHYLENE GLYCOL 著者 Bier, D, Glas, A, Hahne, G, Grossmann, T, Ottmann, C. 登録日 2013-10-15 公開日 2014-02-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction. Angew.Chem.Int.Ed.Engl., 53, 2014
5TPC	Binding domain of BoNT/A complexed with ganglioside 分子名称: Botulinum neurotoxin type A, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose 著者 Berntsson, R.P.-A, Svensson, L.M, Stenmark, P. 登録日 2016-10-20 公開日 2017-01-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Glycans Confer Specificity to the Recognition of Ganglioside Receptors by Botulinum Neurotoxin A. J. Am. Chem. Soc., 139, 2017
4N8S	Crystal Structure of the ternary complex of lipase from Thermomyces lanuginosa with Ethylacetoacetate and P-nitrobenzaldehyde at 2.3 A resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-nitrobenzaldehyde, GLYCEROL, ... 著者 Kumar, M, Mukherjee, J, Gupta, M.N, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. 登録日 2013-10-18 公開日 2013-11-06 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of the ternary complex of lipase from Thermomyces lanuginosa with Ethylacetoacetate and P-nitrobenzaldehyde at 2.3 A resolution To be Published
6JOM	Crystal structure of lipoate protein ligase from Mycoplasma hyopneumoniae 分子名称: 5'-O-[(R)-({5-[(3R)-1,2-DITHIOLAN-3-YL]PENTANOYL}OXY)(HYDROXY)PHOSPHORYL]ADENOSINE, Lipoate--protein ligase 著者 Zhang, H, Chen, H, Ma, G. 登録日 2019-03-22 公開日 2020-03-25 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Functional Identification and Structural Analysis of a New Lipoate Protein Ligase inMycoplasma hyopneumoniae. Front Cell Infect Microbiol, 10, 2020
4NA4	Crystal structure of mouse poly(ADP-ribose) glycohydrolase (PARG) catalytic domain with ADP-HPD 分子名称: 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, IODIDE ION, Poly(ADP-ribose) glycohydrolase 著者 Wang, Z, Cheng, Z, Xu, W. 登録日 2013-10-21 公開日 2014-01-29 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystallographic and biochemical analysis of the mouse poly(ADP-ribose) glycohydrolase. Plos One, 9, 2014
4NB1	Crystal Structure of FosB from Staphylococcus aureus at 1.80 Angstrom Resolution with L-Cysteine-Cys9 Disulfide 分子名称: CYSTEINE, Metallothiol transferase FosB, SULFATE ION 著者 Cook, P.D, Thompson, M.K, Goodman, M.C, Jagessar, K, Harp, J, Keithly, M.E, Armstrong, R.N. 登録日 2013-10-22 公開日 2014-02-26 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure and Function of the Genomically Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus aureus. Biochemistry, 53, 2014
6JLH	Structure of SCGN in complex with a Snap25 peptide 分子名称: CALCIUM ION, CHLORIDE ION, Secretagogin, ... 著者 Qin, J, Sun, Q, Jia, D. 登録日 2019-03-05 公開日 2020-03-11 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Structural and mechanistic insights into secretagogin-mediated exocytosis. Proc.Natl.Acad.Sci.USA, 117, 2020
4N82	X-ray crystal structure of Streptococcus sanguinis NrdIox 分子名称: FLAVIN MONONUCLEOTIDE, Ribonucleotide reductase, SULFATE ION 著者 Boal, A.K, Rosenzweig, A.C. 登録日 2013-10-16 公開日 2014-01-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Streptococcus sanguinis Class Ib Ribonucleotide Reductase: HIGH ACTIVITY WITH BOTH IRON AND MANGANESE COFACTORS AND STRUCTURAL INSIGHTS. J.Biol.Chem., 289, 2014
5MAG	Crystal structure of MELK in complex with an inhibitor 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, Maternal embryonic leucine zipper kinase, ... 著者 Canevari, G, Re Depaolini, S, Casale, E, Felder, E, Kuster, B, Heinzlmeir, S. 登録日 2016-11-03 公開日 2017-12-06 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The target landscape of clinical kinase drugs. Science, 358, 2017
5MGD	STRUCTURE OF E298Q-BETA-GALACTOSIDASE FROM ASPERGILLUS NIGER IN COMPLEX WITH 6-Galactosyl-lactose 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Rico-Diaz, A, Ramirez-Escudero, M, Vizoso Vazquez, A, Cerdan, M.E, Becerra, M, Sanz-Aparicio, J. 登録日 2016-11-21 公開日 2017-04-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural features of Aspergillus niger beta-galactosidase define its activity against glycoside linkages. FEBS J., 284, 2017

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