6JHW

Structure of anti-CRISPR AcrIIC3 and NmeCas9 HNH

Summary for 6JHW

Entry DOI	10.2210/pdb6jhw/pdb
Descriptor	AcrIIC3, CRISPR-associated endonuclease Cas9 (3 entities in total)
Functional Keywords	inhibitor, protein binding, protein binding-hydrolase complex, protein binding/hydrolase
Biological source	Neisseria meningitidis More
Total number of polymer chains	4
Total formula weight	60035.88
Authors	Suh, J.Y.,Lee, B.J.,Lee, S.J.,Kim, Y. (deposition date: 2019-02-19, release date: 2019-08-28, Last modification date: 2023-11-22)
Primary citation	Kim, Y.,Lee, S.J.,Yoon, H.J.,Kim, N.K.,Lee, B.J.,Suh, J.Y. Anti-CRISPR AcrIIC3 discriminates between Cas9 orthologs via targeting the variable surface of the HNH nuclease domain. Febs J., 286:4661-4674, 2019 Cited by PubMed: 31389128 DOI: 10.1111/febs.15037 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.04 Å)

Structure validation