PDB: 1957 件ウェブページステータス検索Chemie searchBIRD

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7V1D	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH and GpppA) 分子名称: Core protein, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7V1I	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (with an m7GMP-Arg28 adduct and in complex with SAH) 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Core protein, GLYCEROL, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7V1G	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (with a GMP-Arg28 adduct and in complex with SAM) 分子名称: CITRIC ACID, Core protein, GLYCEROL, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7V1C	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SIN) 分子名称: Core protein, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7V1E	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH and m7GpppAmG) 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-ADENOSINE, Core protein, GLYCEROL, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7V1F	Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAM and GTP) 分子名称: Core protein, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Jia, H, Gong, P. 登録日 2021-08-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct. J.Virol., 96, 2022
7NBV	Structure of 2A protein from Theilers murine encephalomyelitis virus (TMEV) 分子名称: BROMIDE ION, Capsid protein VP0 著者 Hill, C.H, Cook, G.M, Napthine, S, Kibe, A, Brown, K, Caliskan, N, Firth, A.E, Graham, S.C, Brierley, I. 登録日 2021-01-28 公開日 2021-12-08 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Investigating molecular mechanisms of 2A-stimulated ribosomal pausing and frameshifting in Theilovirus. Nucleic Acids Res., 49, 2021
5O19	Japanese encephalitis virus non-structural protein 1 C-terminal domain 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Genome polyprotein, SULFATE ION 著者 Poonsiri, T, Wright, G.S.A, Antonyuk, S.V. 登録日 2017-05-18 公開日 2018-01-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Study of the C-Terminal Domain of Nonstructural Protein 1 from Japanese Encephalitis Virus. J. Virol., 92, 2018
1EAH	PV2L COMPLEXED WITH ANTIVIRAL AGENT SCH48973 分子名称: 1[2-CHLORO-4-METHOXY-PHENYL-OXYMETHYL]-4-[2,6-DICHLORO-PHENYL-OXYMETHYL]-BENZENE, MYRISTIC ACID, POLIOVIRUS TYPE 2 COAT PROTEINS VP1 TO VP4 著者 Lentz, K, Arnold, E. 登録日 1997-07-22 公開日 1998-09-16 最終更新日 2023-04-19 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of poliovirus type 2 Lansing complexed with antiviral agent SCH48973: comparison of the structural and biological properties of three poliovirus serotypes. Structure, 5, 1997
6EUV	Structure of the midlink and cap-binding domains of influenza A polymerase PB2 subunit with a bound azaindole cap-binding inhibitor (VX-787) 分子名称: (2S,3S)-3-[[5-fluoranyl-2-(5-fluoranyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, NICKEL (II) ION, Polymerase basic protein 2 著者 Cusack, S, Lethier, M. 登録日 2017-10-31 公開日 2017-12-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors. Nucleic Acids Res., 46, 2018
6EUY	Structure of the midlink and cap-binding domains of influenza A polymerase PB2 subunit with a bound azaindazole cap-binding inhibitor 分子名称: (2~{S},3~{S})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-yl]amino]bicyclo[2.2.2]octane-2-carboxylic acid, Polymerase basic protein 2, SULFATE ION 著者 Cusack, S, Gaudon, S. 登録日 2017-10-31 公開日 2017-12-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors. Nucleic Acids Res., 46, 2018
7T17	Zika Virus asymmetric unit bound with IgM antibody DH1017 Fab fragment 分子名称: Core protein, DH1017.IgM FabC constant domain, DH1017.IgM IgH, ... 著者 Miller, A.S, Kuhn, R.J. 登録日 2021-12-01 公開日 2022-11-23 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (5.26 Å) 主引用文献 A Zika virus-specific IgM elicited in pregnancy exhibits ultrapotent neutralization. Cell, 185, 2022
3JD7	The novel asymmetric entry intermediate of a picornavirus captured with nanodiscs 分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... 著者 Lee, H, Shingler, K.L, Organtini, L.J, Ashley, R.E, Makhov, A.M, Conway, J.F, Hafenstein, S. 登録日 2016-04-29 公開日 2016-09-14 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 The novel asymmetric entry intermediate of a picornavirus captured with nanodiscs. Sci Adv, 2, 2016
6G0R	Crystal Structure of the first bromodomain of human BRD4 in complex with an acetylated POLR2A peptide (K775ac/K778ac) 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, DNA-directed RNA polymerase II subunit RPB1 著者 Filippakopoulos, P, Picaud, S, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C. 登録日 2018-03-19 公開日 2018-11-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains. Mol. Cell, 73, 2019
7WUV	CryoEM structure of sNS1 hexamer 分子名称: Core protein 著者 Shu, B, Ooi, J.S.G, Lok, S.M. 登録日 2022-02-09 公開日 2022-12-21 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever. Nat Commun, 13, 2022
7WUT	CryoEM structure of stable sNS1 tetramer 分子名称: Core protein 著者 Shu, B, Ooi, J.S.G, Lok, S.M. 登録日 2022-02-09 公開日 2022-12-21 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever. Nat Commun, 13, 2022
3P8O	Crystal structure of HCV NS3/NS4A protease complexed with des-bromine analogue of BI 201335 分子名称: HCV non-structural protein 4A, HCV serine protease NS3, N-[(cyclopentyloxy)carbonyl]-3-methyl-L-valyl-(4R)-N-[(1R,2S)-1-carboxy-2-ethenylcyclopropyl]-4-[(7-methoxy-2-{2-[(2-methylpropanoyl)amino]-1,3-thiazol-4-yl}quinolin-4-yl)oxy]-L-prolinamide, ... 著者 Lemke, C.T. 登録日 2010-10-14 公開日 2011-01-26 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Combined X-ray, NMR, and kinetic analyses reveal uncommon binding characteristics of the hepatitis C virus NS3-NS4A protease inhibitor BI 201335. J.Biol.Chem., 286, 2011
3P8N	Crystal structure of HCV NS3/NS4A protease complexed with BI 201335 分子名称: HCV non-structural protein 4A, HCV serine protease NS3, N-[(cyclopentyloxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[(8-bromo-7-methoxy-2-{2-[(2-methylpropanoyl)amino]-1,3-thiazol-4-yl}quinolin-4-yl)oxy]-N-[(1R,2S)-1-carboxy-2-ethenylcyclopropyl]-L-prolinamide, ... 著者 Lemke, C.T. 登録日 2010-10-14 公開日 2011-01-26 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Combined X-ray, NMR, and kinetic analyses reveal uncommon binding characteristics of the hepatitis C virus NS3-NS4A protease inhibitor BI 201335. J.Biol.Chem., 286, 2011
1HRV	HRV14/SDZ 35-682 COMPLEX 分子名称: 1-[2-HYDROXY-3-(4-CYCLOHEXYL-PHENOXY)-PROPYL]-4-(2-PYRIDYL)-PIPERAZINE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ... 著者 Oren, D.A, Zhang, A, Arnold, E. 登録日 1995-03-02 公開日 1995-06-03 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 SDZ 35-682, a new picornavirus capsid-binding agent with potent antiviral activity. Antiviral Res., 26, 1995
2FP7	West Nile Virus NS2B/NS3protease in complex with Bz-Nle-Lys-Arg-Arg-H 分子名称: Genome polyprotein, N-benzoyl-L-norleucyl-L-lysyl-N-[(2S)-5-carbamimidamido-1-hydroxypentan-2-yl]-L-argininamide 著者 Schiering, N, D'Arcy, A, Erbel, P. 登録日 2006-01-16 公開日 2006-03-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus. Nat.Struct.Mol.Biol., 13, 2006
3LKW	Crystal Structure of Dengue Virus 1 NS2B/NS3 protease active site mutant 分子名称: CADMIUM ION, CHLORIDE ION, GLYCEROL, ... 著者 Chandramouli, S, Joseph, J.S, Daudenarde, S, Gatchalian, J, Cornillez-Ty, C, Kuhn, P. 登録日 2010-01-28 公開日 2010-03-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Serotype-specific structural differences in the protease-cofactor complexes of the dengue virus family. J.Virol., 84, 2010
7MWX	Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2 with tamarin CD81 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2A12 Fab Heavy Chain, ... 著者 Kumar, A, Hossain, R.A, Yost, S.A, Bu, W, Wang, Y, Dearborn, A.D, Grakoui, A, Cohen, J.I, Marcotrigiano, J. 登録日 2021-05-17 公開日 2021-09-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.32 Å) 主引用文献 Structural insights into hepatitis C virus receptor binding and entry. Nature, 598, 2021
7MWW	Structure of hepatitis C virus envelope full-length glycoprotein 2 (eE2) from J6 genotype 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2A12 Fab Heavy chain, ... 著者 Kumar, A, Hossain, R.A, Yost, S.A, Bu, W, Wang, Y, Dearborn, A.D, Grakoui, A, Cohen, J.I, Marcotrigiano, J. 登録日 2021-05-17 公開日 2021-09-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Structural insights into hepatitis C virus receptor binding and entry. Nature, 598, 2021
3L6P	Crystal Structure of Dengue Virus 1 NS2B/NS3 protease 分子名称: CADMIUM ION, NICKEL (II) ION, SULFATE ION, ... 著者 Chandramouli, S, Joseph, J.S, Daudenarde, S, Gatchalian, J, Cornillez-Ty, C, Kuhn, P. 登録日 2009-12-23 公開日 2010-03-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Serotype-specific structural differences in the protease-cofactor complexes of the dengue virus family. J.Virol., 84, 2010
1OKE	Crystal structure of the dengue 2 virus envelope protein in complex with n-octyl-beta-D-glucoside 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAJOR ENVELOPE PROTEIN E, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Modis, Y, Harrison, S.C. 登録日 2003-07-22 公開日 2003-07-24 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A Ligand-Binding Pocket in the Dengue Virus Envelope Glycoprotein. Proc.Natl.Acad.Sci.USA, 100, 2003

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