PDB: 19260 件ウェブページステータス検索Chemie searchBIRD

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3Q7V	Beta-Lactam-Sensor Domain of BlaR1 (Apo) from Staphylococcus Aureus with Carboxylated Lys392 分子名称: Beta-lactamase regulatory protein BlaR1, GLYCEROL, SULFATE ION 著者 Borbulevych, O.Y, Mobashery, S, Baker, B.M. 登録日 2011-01-05 公開日 2011-06-29 最終更新日 2013-01-09 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Lysine Nzeta-decarboxylation switch and activation of the beta-lactam sensor domain of BlaR1 protein of methicillin-resistant Staphylococcus aureus. J.Biol.Chem., 286, 2011
3QLD	Structure of Probable Mandelate Racemase (AaLAA1DRAFT_2112) from Alicyclobacillus Acidocaldarius 分子名称: Mandelate racemase/muconate lactonizing protein, SULFATE ION 著者 Ramagopal, U.A, Toro, R, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2011-02-02 公開日 2011-04-27 最終更新日 2021-02-10 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of Probable Mandelate Racemase (AaLAA1DRAFT_2112) from Alicyclobacillus Acidocaldarius To be published
3Q9C	Crystal Structure of H159A APAH complexed with N8-acetylspermidine 分子名称: Acetylpolyamine amidohydrolase, N-{4-[(3-aminopropyl)amino]butyl}acetamide, POTASSIUM ION, ... 著者 Lombardi, P.M, Christianson, D.W. 登録日 2011-01-07 公開日 2011-03-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of prokaryotic polyamine deacetylase reveals evolutionary functional relationships with eukaryotic histone deacetylases . Biochemistry, 50, 2011
3QB1	Interleukin-2 mutant D10 分子名称: Interleukin-2 著者 Levin, A.M, Bates, D.L, Ring, A.M, Lin, J.T, Su, L, Krieg, C, Bowman, G.R, Novick, P, Pande, V.S, Khort, H.E, Boyman, O, Fathman, C.G, Garcia, K.C. 登録日 2011-01-12 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Exploiting a natural conformational switch to engineer an interleukin-2 'superkine' Nature, 484, 2012
3QNZ	Orthorhombic form of IgG1 Fab fragment (in complex with antigenic tubulin peptide) sharing same Fv as IgA 分子名称: Fab fragment of IMMUNOGLOBULIN G1 HEAVY CHAIN, Fab fragment of IMMUNOGLOBULIN G1 LIGHT CHAIN, GLYCEROL, ... 著者 Trajtenberg, F, Correa, A, Buschiazzo, A. 登録日 2011-02-09 公開日 2012-02-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of a human IgA1 Fab fragment at 1.55 angstrom resolution: potential effect of the constant domains on antigen-affinity modulation Acta Crystallogr.,Sect.D, 69, 2013
3QO6	Crystal structure analysis of the plant protease Deg1 分子名称: Protease Do-like 1, chloroplastic, peptide 著者 Clausen, T. 登録日 2011-02-09 公開日 2011-05-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural adaptation of the plant protease Deg1 to repair photosystem II during light exposure. Nat.Struct.Mol.Biol., 18, 2011
3QCJ	Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 5-[({3-[(3,4-dichlorobenzyl)sulfanyl]thiophen-2-yl}carbonyl)sulfamoyl]-2-methoxybenzoic acid 分子名称: 5-[({3-[(3,4-dichlorobenzyl)sulfanyl]thiophen-2-yl}carbonyl)sulfamoyl]-2-methoxybenzoic acid, Receptor-type tyrosine-protein phosphatase gamma 著者 Sheriff, S. 登録日 2011-01-16 公開日 2011-12-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop J.Med.Chem., 54, 2011
3QPP	Structure of PDE10-inhibitor complex 分子名称: 7-methoxy-4-[(3S)-3-phenylpiperidin-1-yl]-6-[2-(quinolin-2-yl)ethoxy]quinazoline, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... 著者 Pandit, J, Marr, E.S. 登録日 2011-02-14 公開日 2011-06-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Use of Structure-Based Design to Discover a Potent, Selective, In Vivo Active Phosphodiesterase 10A Inhibitor Lead Series for the Treatment of Schizophrenia. J.Med.Chem., 54, 2011
3QQ8	Crystal structure of p97-N in complex with FAF1-UBX 分子名称: CHLORIDE ION, FAS-associated factor 1, Transitional endoplasmic reticulum ATPase 著者 Haenzelmann, P, Schindelin, H. 登録日 2011-02-15 公開日 2011-06-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Hierarchical Binding of Cofactors to the AAA ATPase p97. Structure, 19, 2011
3QDG	The complex between TCR DMF5 and human Class I MHC HLA-A2 with the bound MART-1(26-35)(A27L) peptide 分子名称: Beta-2-microglobulin, DMF5 alpha chain, DMF5 beta chain, ... 著者 Borbulevych, O.Y, Baker, B.M. 登録日 2011-01-18 公開日 2011-07-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms. J.Immunol., 187, 2011
3Q5S	Crystal structure of BmrR bound to Acetylcholine 分子名称: 23 bp promoter DNA, ACETYLCHOLINE, GLYCEROL, ... 著者 Bachas, S, Eginton, C, Gunio, G, Wade, H. 登録日 2010-12-29 公開日 2011-06-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proc.Natl.Acad.Sci.USA, 108, 2011
3Q7I	Glucose-6-phosphate isomerase from Francisella tularensis complexed with 6-phosphogluconic acid. 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-PHOSPHOGLUCONIC ACID, CALCIUM ION, ... 著者 Osipiuk, J, Maltseva, N, Hasseman, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2011-01-04 公開日 2011-02-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Glucose-6-phosphate isomerase from Francisella tularensis. To be Published
3Q8H	Crystal structure of 2c-methyl-d-erythritol 2,4-cyclodiphosphate synthase from burkholderia pseudomallei in complex with cytidine derivative EBSI01028 分子名称: 1,2-ETHANEDIOL, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 5'-deoxy-5'-[(imidazo[2,1-b][1,3]thiazol-5-ylcarbonyl)amino]cytidine, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-01-06 公開日 2011-01-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Cytidine derivatives as IspF inhibitors of Burkolderia pseudomallei. Bioorg.Med.Chem.Lett., 23, 2013
3QGD	Crystal structure of the hepatitis C virus NS5B RNA-dependent RNA polymerase complex with (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid and (2R)-4-(2,6-dimethoxypyrimidin-4-yl)-1-[(4-ethylphenyl)sulfonyl]-N-(4-methoxybenzyl)piperazine-2-carboxamide 分子名称: (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid, (2R)-4-(2,6-dimethoxypyrimidin-4-yl)-1-[(4-ethylphenyl)sulfonyl]-N-(4-methoxybenzyl)piperazine-2-carboxamide, RNA-directed RNA polymerase, ... 著者 Sheriff, S. 登録日 2011-01-24 公開日 2011-04-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Investigation of the mode of binding of a novel series of N-benzyl-4-heteroaryl-1-(phenylsulfonyl)piperazine-2-carboxamides to the hepatitis C virus polymerase. Bioorg.Med.Chem.Lett., 21, 2011
3QAH	Crystal structure of apo-form human MOF catalytic domain 分子名称: Probable histone acetyltransferase MYST1, ZINC ION 著者 Sun, B, Tang, Q, Zhong, C, Ding, J. 登録日 2011-01-11 公開日 2011-07-06 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Regulation of the histone acetyltransferase activity of hMOF via autoacetylation of Lys274 Cell Res., 21, 2011
3QCB	Human receptor protein tyrosine phosphatase gamma, domain 1, apo 分子名称: Receptor-type tyrosine-protein phosphatase gamma, SULFATE ION 著者 Sheriff, S. 登録日 2011-01-16 公開日 2011-12-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop J.Med.Chem., 54, 2011
3QHD	Crystal structure of 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE Synthase from BURKHOLDERIA PSEUDOMALLEI bound to CYTIDINE, FOL795 and FOL955 分子名称: 2-(pyridin-3-yl)-1,3-thiazole-4-carbaldehyde, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 4-(1H-IMIDAZOL-1-YL)PHENOL, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-01-25 公開日 2011-02-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12, 2011
3QHW	Structure of a pCDK2/CyclinA transition-state mimic 分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, CDK2 substrate peptide: PKTPKKAKKL, ... 著者 Young, M.A, Jacobsen, D.M, Bao, Z.Q. 登録日 2011-01-26 公開日 2011-05-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Briefly Bound to Activate: Transient Binding of a Second Catalytic Magnesium Activates the Structure and Dynamics of CDK2 Kinase for Catalysis. Structure, 19, 2011
3QD0	Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with (2R,5S)-1-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-6-methyl-N-phenyl-3-piperidinecarboxamide 分子名称: (3S,6R)-1-[2-amino-6-(3-amino-2H-indazol-6-yl)pyrimidin-4-yl]-6-methyl-N-phenylpiperidine-3-carboxamide, 3-phosphoinositide-dependent protein kinase 1, GLYCEROL, ... 著者 Medina, J.R, Becker, C.J, Blackledge, C.W, Duquenne, C, Feng, Y, Grant, S.W, Heerding, D, Li, W.H, Miller, W.H, Romeril, S.P, Scherzer, D, Shu, A, Bobko, M.A, Chadderton, A.R, Dumble, M, Gradiner, C.M, Gilbert, S, Liu, Q, Rabindran, S.K, Sudakin, V, Xiang, H, Brady, P.G, Campobasso, N, Ward, P, Axten, J.M. 登録日 2011-01-17 公開日 2011-03-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structure-Based Design of Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Inhibitors. J.Med.Chem., 54, 2011
3QDL	Crystal structure of RdxA from Helicobacter pyroli 分子名称: FLAVIN MONONUCLEOTIDE, GLYCEROL, Oxygen-insensitive NADPH nitroreductase 著者 Rojas, A.L, Martinez-Julvez, M, Olekhnovich, I.N, Hoffman, P.S, Sancho, J. 登録日 2011-01-18 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of RdxA--an oxygen-insensitive nitroreductase essential for metronidazole activation in Helicobacter pylori. Febs J., 279, 2012
3QIU	Crystal structure of the 226 TCR in complex with MCC/I-Ek 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, E-K alpha chain, ... 著者 Kruse, A.C, Ely, L.K, Newell, E.W, Davis, M.M, Garcia, K.C. 登録日 2011-01-27 公開日 2011-04-27 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k). J.Immunol., 186, 2011
3QJA	Crystal Structure of the Mycobacterium tuberculosis Indole-3-glycerol phosphate synthase (TrpC) in apo form 分子名称: Indole-3-glycerol phosphate synthase, SULFATE ION 著者 Reddy, M.C.M, Bruning, J.B, Thurman, C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2011-01-28 公開日 2011-06-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 Small-molecule scaffolds for Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) inhibitors identified by high-throughput screening and defined by X-ray crystallography To be Published
3QKX	Crystal structure of a TetR-family transcriptional regulator (HI0893) from Haemophilus influenzae RD at 2.35 A resolution 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-02-01 公開日 2011-03-02 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structure of a TetR-family transcriptional regulator (HI0893) from Haemophilus influenzae RD at 2.35 A resolution To be published
3QGJ	1.3A Structure of alpha-Lytic Protease Bound to Ac-AlaAlaPro-Alanal 分子名称: 1,2-ETHANEDIOL, Ac-AlaAlaPro-Alanal peptide, Alpha-lytic protease, ... 著者 Everill, P, Meinke, G, Bohm, A, Bachovchin, W. 登録日 2011-01-24 公開日 2012-02-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Substrate Binding Defines Ser195 Position in the Catalytic Triad of Serine Proteases, Not His57 protonation To be Published
3R0R	The 2.3 A structure of porcine circovirus 2 分子名称: Porcine circovirus 2 (PCV2) capsid protein, SULFATE ION 著者 Khayat, R, Speir, J.A, Johnson, J.E. 登録日 2011-03-08 公開日 2011-06-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The 2.3-angstrom structure of porcine circovirus 2. J.Virol., 85, 2011

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