Crystal structure of BmrR bound to Acetylcholine

Summary for 3Q5S

Related3D6Y 3D6Z 3Q1M 3Q2Y 3Q5P 3Q5R
DescriptorMultidrug-efflux transporter 1 regulator, 23 bp promoter DNA, ACETYLCHOLINE, ... (5 entities in total)
Functional Keywordsmultidrug binding, multidrug resistance, transcription regulator, transcription-dna complex, transcription/dna
Biological sourceBacillus subtilis
Total number of polymer chains2
Total molecular weight40775.04
Bachas, S.,Eginton, C.,Gunio, G.,Wade, H. (deposition date: 2010-12-29, release date: 2011-06-15, Last modification date: 2017-11-08)
Primary citation
Bachas, S.,Eginton, C.,Gunio, D.,Wade, H.
Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR.
Proc.Natl.Acad.Sci.USA, 108:11046-11051, 2011
PubMed: 21690368 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1104850108
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2752302.5%0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload