3QHW
Structure of a pCDK2/CyclinA transition-state mimic
Summary for 3QHW
Entry DOI | 10.2210/pdb3qhw/pdb |
Related | 3QHR |
Descriptor | Cell division protein kinase 2, Cyclin-A2, CDK2 substrate peptide: PKTPKKAKKL, ... (9 entities in total) |
Functional Keywords | kinase catalytic domain, protein kinase, cyclin, phosphorylated thr-160, phosphorylated on thr-160, transferase-protein binding complex, transferase/protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P51943 |
Total number of polymer chains | 8 |
Total formula weight | 133702.89 |
Authors | Young, M.A.,Jacobsen, D.M.,Bao, Z.Q. (deposition date: 2011-01-26, release date: 2011-05-25, Last modification date: 2024-04-03) |
Primary citation | Bao, Z.Q.,Jacobsen, D.M.,Young, M.A. Briefly Bound to Activate: Transient Binding of a Second Catalytic Magnesium Activates the Structure and Dynamics of CDK2 Kinase for Catalysis. Structure, 19:675-690, 2011 Cited by PubMed: 21565702DOI: 10.1016/j.str.2011.02.016 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.91 Å) |
Structure validation
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