3QHD

Crystal structure of 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE Synthase from BURKHOLDERIA PSEUDOMALLEI bound to CYTIDINE, FOL795 and FOL955

Summary for 3QHD

Entry DOI	10.2210/pdb3qhd/pdb
Related	3f0d 3ieq 3ike 3mbm 3p0z 3p10
Descriptor	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, CHLORIDE ION, ... (8 entities in total)
Functional Keywords	seattle structural genomics center for infectious disease, ssgcid, ispf, cytidine, fol795, fol955, mep pathway, lyase, metal-binding
Biological source	Burkholderia pseudomallei
Total number of polymer chains	3
Total formula weight	59812.15
Authors	Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2011-01-25, release date: 2011-02-09, Last modification date: 2023-09-13)
Primary citation	Begley, D.W.,Hartley, R.C.,Davies, D.R.,Edwards, T.E.,Leonard, J.T.,Abendroth, J.,Burris, C.A.,Bhandari, J.,Myler, P.J.,Staker, B.L.,Stewart, L.J. Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12:63-76, 2011 Cited by PubMed: 21359640 DOI: 10.1007/s10969-011-9102-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation