3PKN
| Crystal structure of MLLE domain of poly(A) binding protein in complex with PAM2 motif of La-related protein 4 (LARP4) | 分子名称: | IODIDE ION, La-related protein 4, Polyadenylate-binding protein 1, ... | 著者 | Xie, J, Kozlov, G, Gehring, K. | 登録日 | 2010-11-11 | 公開日 | 2011-01-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | La-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA Stability. Mol.Cell.Biol., 31, 2011
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4JZS
| Crystal structure of the Bacillus subtilis pyrophosphohydrolase BsRppH (E68A mutant) | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, dGTP pyrophosphohydrolase | 著者 | Piton, J, Larue, V, Thillier, Y, Dorleans, A, Pellegrini, O, Li de la Sierra-Gallay, I, Vasseur, J.J, Debart, F, Tisne, C, Condon, C. | 登録日 | 2013-04-03 | 公開日 | 2013-05-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates. Proc.Natl.Acad.Sci.USA, 110, 2013
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4JZU
| Crystal structure of the Bacillus subtilis pyrophosphohydrolase BsRppH bound to a non-hydrolysable triphosphorylated dinucleotide RNA (pcp-pGpG) - first guanosine residue in guanosine binding pocket | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, RNA (5'-R(*(GCP)P*G)-3'), RNA PYROPHOSPHOHYDROLASE | 著者 | Piton, J, Larue, V, Thillier, Y, Dorleans, A, Pellegrini, O, Li de la Sierra-Gallay, I, Vasseur, J.J, Debart, F, Tisne, C, Condon, C. | 登録日 | 2013-04-03 | 公開日 | 2013-05-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates. Proc.Natl.Acad.Sci.USA, 110, 2013
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3PMK
| Crystal structure of the Vesicular Stomatitis Virus RNA free nucleoprotein/phosphoprotein complex | 分子名称: | Nucleocapsid protein, Phosphoprotein | 著者 | Leyrat, C, Yabukarski, F, Tarbouriech, N, Ruigrok, R.W.H, Jamin, M. | 登録日 | 2010-11-17 | 公開日 | 2011-10-05 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | Structure of the Vesicular Stomatitis Virus N0-P Complex Plos Pathog., 7, 2011
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8R3B
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6VWB
| Solution structure of the N-terminal helix-hairpin-helix domain of human MUS81 | 分子名称: | Crossover junction endonuclease MUS81 | 著者 | Payliss, B, Houliston, S, Lemak, A, Arrowsmith, C.H, Wyatt, H.D.M. | 登録日 | 2020-02-19 | 公開日 | 2021-02-24 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Phosphorylation of the DNA repair scaffold SLX4 drives folding of the SAP domain and activation of the MUS81-EME1 endonuclease Cell Rep, 41, 2022
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6VZC
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6W9N
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8RC1
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3PT3
| Crystal structure of the C-terminal lobe of the human UBR5 HECT domain | 分子名称: | E3 ubiquitin-protein ligase UBR5 | 著者 | Matta-Camacho, E, Kozlov, G, Menade, M, Gehring, K. | 登録日 | 2010-12-02 | 公開日 | 2012-01-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Structure of the HECT C-lobe of the UBR5 E3 ubiquitin ligase. Acta Crystallogr.,Sect.F, 68, 2012
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8PXS
| Short RNA binding to peptide amyloids | 分子名称: | RNA (5'-R(P*GP*UP*CP*A)-3'), VAL-ALA-GLN-ALA-GLN-ILE-ASN-ILE | 著者 | Rout, S.K, Cadalbert, R, Schroder, N, Wiegand, T, Zehnder, J, Gampp, O, Guntert, P, Kringler, D, Kreutz, C, Knorlein, A, Hall, J, Greenwald, J, Riek, R. | 登録日 | 2023-07-24 | 公開日 | 2023-10-18 | 実験手法 | SOLID-STATE NMR | 主引用文献 | An Analysis of Nucleotide-Amyloid Interactions Reveals Selective Binding to Codon-Sized RNA. J.Am.Chem.Soc., 145, 2023
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3M4N
| Crystal structure of N-acetyl-L-ornithine transcarbamylase K302A mutant complexed with PALAO | 分子名称: | N-acetylornithine carbamoyltransferase, N~2~-acetyl-N~5~-(phosphonoacetyl)-L-ornithine, SULFATE ION | 著者 | Li, Y, Yu, X, Allewell, N.M, Tuchman, M, Shi, D. | 登録日 | 2010-03-11 | 公開日 | 2010-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Reversible post-translational carboxylation modulates the enzymatic activity of N-acetyl-L-ornithine transcarbamylase. Biochemistry, 49, 2010
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8QHM
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3M94
| Complex crystal structure of Ascaris suum eIF4E-3 with m2,2,7G cap | 分子名称: | ACETYL GROUP, Eukaryotic translation initiation factor 4E-binding protein 1, N,N,7-trimethylguanosine 5'-(trihydrogen diphosphate), ... | 著者 | Liu, W, Berkeley Structural Genomics Center (BSGC) | 登録日 | 2010-03-19 | 公開日 | 2011-07-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural basis for nematode eIF4E binding an m2,2,7G-Cap and its implications for translation initiation. Nucleic Acids Res., 39, 2011
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4H6I
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3MBG
| Crystal Structure of Human Augmenter of Liver Regeneration (ALR) | 分子名称: | ACETATE ION, FAD-linked sulfhydryl oxidase ALR, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Dong, M, Schaefer, S, Daithankar, V.N, Thorpe, C, Bahnson, B.J. | 登録日 | 2010-03-25 | 公開日 | 2010-07-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of the human sulfhydryl oxidase augmenter of liver regeneration and characterization of a human mutation causing an autosomal recessive myopathy . Biochemistry, 49, 2010
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8TWI
| Cryo-EM structure of the PP2A:B55-FAM122A complex, PP2Ac body | 分子名称: | FE (III) ION, PPP2R1A-PPP2R2A-interacting phosphatase regulator 1, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... | 著者 | Fuller, J.R, Padi, S.K.R, Peti, W, Page, R. | 登録日 | 2023-08-21 | 公開日 | 2023-11-01 | 最終更新日 | 2024-01-17 | 実験手法 | ELECTRON MICROSCOPY (2.69 Å) | 主引用文献 | Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. Nature, 625, 2024
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8TWE
| Cryo-EM structure of the PP2A:B55-FAM122A complex, B55 body | 分子名称: | PPP2R1A-PPP2R2A-interacting phosphatase regulator 1, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... | 著者 | Fuller, J.R, Padi, S.K.R, Peti, W, Page, R. | 登録日 | 2023-08-21 | 公開日 | 2023-11-01 | 最終更新日 | 2024-01-17 | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | 主引用文献 | Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. Nature, 625, 2024
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8TTB
| Cryo-EM structure of the PP2A:B55-ARPP19 complex | 分子名称: | FE (III) ION, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... | 著者 | Fuller, J.R, Padi, S.K.R, Peti, W, Page, R. | 登録日 | 2023-08-13 | 公開日 | 2023-10-25 | 最終更新日 | 2024-01-17 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. Nature, 625, 2024
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4IBE
| Ebola virus VP35 bound to small molecule | 分子名称: | 5-[(2R)-3-benzoyl-2-(4-bromothiophen-2-yl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl]-2-chlorobenzoic acid, GLYCEROL, Polymerase cofactor VP35 | 著者 | Brown, C.S, Leung, D.W, Xu, W, Borek, D.M, Otwinowski, Z, Ramanan, P, Stubbs, A.J, Peterson, D.S, Binning, J.M, Amarasinghe, G.K, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2012-12-08 | 公開日 | 2014-03-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity. J.Mol.Biol., 426, 2014
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4IN4
| Crystal structure of cpd 15 bound to Keap1 Kelch domain | 分子名称: | 2-({5-[(2,4-dimethylphenyl)sulfonyl]-6-oxo-1,6-dihydropyrimidin-2-yl}sulfanyl)-N-[2-(trifluoromethyl)phenyl]acetamide, Kelch-like ECH-associated protein 1, PHOSPHATE ION | 著者 | Silvian, L, Marcotte, D. | 登録日 | 2013-01-03 | 公開日 | 2013-05-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism. Bioorg.Med.Chem., 21, 2013
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6X7B
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4ICT
| Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121 | 分子名称: | (3S,6S)-3-benzyl-6-(4-hydroxybenzyl)piperazine-2,5-dione, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Fonvielle, M, Le Du, M.-H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P. | 登録日 | 2012-12-11 | 公開日 | 2013-05-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES. J.Biol.Chem., 288, 2013
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4IBF
| Ebola virus VP35 bound to small molecule | 分子名称: | (4-{(2R)-2-(4-bromothiophen-2-yl)-3-[(5-chlorothiophen-2-yl)carbonyl]-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl}phenyl)acetic acid, Polymerase cofactor VP35 | 著者 | Brown, C.S, Leung, D.W, Xu, W, Borek, D.M, Otwinowski, Z, Ramanan, P, Stubbs, A.J, Peterson, D.S, Binning, J.M, Amarasinghe, G.K, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2012-12-08 | 公開日 | 2014-03-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.291 Å) | 主引用文献 | In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity. J.Mol.Biol., 426, 2014
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6X7C
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