8TWI
Cryo-EM structure of the PP2A:B55-FAM122A complex, PP2Ac body
Summary for 8TWI
Entry DOI | 10.2210/pdb8twi/pdb |
Related | 8SO0 |
EMDB information | 40644 41668 |
Descriptor | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PPP2R1A-PPP2R2A-interacting phosphatase regulator 1, ... (5 entities in total) |
Functional Keywords | protein phosphatase 2a:b55 holoenzyme fam122a inhibitor substrate binding cell cycle regulation, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 111605.52 |
Authors | Fuller, J.R.,Padi, S.K.R.,Peti, W.,Page, R. (deposition date: 2023-08-21, release date: 2023-11-01, Last modification date: 2024-01-17) |
Primary citation | Padi, S.K.R.,Vos, M.R.,Godek, R.J.,Fuller, J.R.,Kruse, T.,Hein, J.B.,Nilsson, J.,Kelker, M.S.,Page, R.,Peti, W. Cryo-EM structures of PP2A:B55-FAM122A and PP2A:B55-ARPP19. Nature, 625:195-203, 2024 Cited by PubMed: 38123684DOI: 10.1038/s41586-023-06870-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.69 Å) |
Structure validation
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