3PKN

Crystal structure of MLLE domain of poly(A) binding protein in complex with PAM2 motif of La-related protein 4 (LARP4)

Summary for 3PKN

• Entry DOI: 10.2210/pdb3pkn/pdb
• Descriptor: Polyadenylate-binding protein 1, La-related protein 4, SULFATE ION, ... (5 entities in total)
• Functional Keywords: all helical domain, protein binding, la-related protein 4
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P11940
• Total number of polymer chains: 2
• Total formula weight: 11186.60

Authors

Xie, J.,Kozlov, G.,Gehring, K. (deposition date: 2010-11-11, release date: 2011-01-12, Last modification date: 2023-09-06)

• Primary citation: Yang, R.,Gaidamakov, S.A.,Xie, J.,Lee, J.,Martino, L.,Kozlov, G.,Crawford, A.K.,Russo, A.N.,Conte, M.R.,Gehring, K.,Maraia, R.J.; La-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA Stability.; Mol.Cell.Biol., 31:542-556, 2011; PubMed: 21098120; DOI: 10.1128/MCB.01162-10

Experimental method

X-RAY DIFFRACTION (1.8 Å)