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6W9N

Solution structure of the FYVE domain of ALFY

Summary for 6W9N
Entry DOI10.2210/pdb6w9n/pdb
NMR InformationBMRB: 30736
DescriptorWD repeat and FYVE domain-containing protein 3, ZINC ION (2 entities in total)
Functional Keywordsfyve domain, phosphoinositide binding, zinc binding, lipid binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight9070.89
Authors
Reinhart, E.F.,Pellegrini, M.,Ragusa, M.J. (deposition date: 2020-03-23, release date: 2020-12-23, Last modification date: 2023-06-14)
Primary citationReinhart, E.F.,Litt, N.A.,Katzenell, S.,Pellegrini, M.,Yamamoto, A.,Ragusa, M.J.
A highly conserved glutamic acid in ALFY inhibits membrane binding to aid in aggregate clearance.
Traffic, 22:23-37, 2021
Cited by
PubMed: 33225481
DOI: 10.1111/tra.12771
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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