5C0A
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![BU of 5c0a by Molmil](/molmil-images/mine/5c0a) | 1E6 TCR in complex with HLA-A02 carrying MVW peptide | 分子名称: | 1,2-ETHANEDIOL, 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, ... | 著者 | Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. | 登録日 | 2015-06-12 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J.Clin.Invest., 126, 2016
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4JFD
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![BU of 4jfd by Molmil](/molmil-images/mine/4jfd) | Preservation of peptide specificity during TCR-MHC contact dominated affinity enhancement of a melanoma-specific TCR | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | 著者 | Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K. | 登録日 | 2013-02-28 | 公開日 | 2013-05-29 | 最終更新日 | 2013-07-17 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | T-cell receptor specificity maintained by altered thermodynamics. J.Biol.Chem., 288, 2013
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5C09
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![BU of 5c09 by Molmil](/molmil-images/mine/5c09) | HLA class I histocompatibility antigen | 分子名称: | 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, Beta-2-microglobulin, ... | 著者 | Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. | 登録日 | 2015-06-12 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.475 Å) | 主引用文献 | Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J.Clin.Invest., 126, 2016
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6AZK
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![BU of 6azk by Molmil](/molmil-images/mine/6azk) | |
8KB0
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![BU of 8kb0 by Molmil](/molmil-images/mine/8kb0) | Crystal structure of 01JD-AEAIIVAMV | 分子名称: | Beta2-microglobulin, MHC class I antigen alpha chain, peptide of AIV | 著者 | Tang, Z, Zhang, N. | 登録日 | 2023-08-03 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | The impact of micropolymorphism in Anpl-UAA on structural stability and peptide presentation. Int.J.Biol.Macromol., 267, 2024
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4WW2
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![BU of 4ww2 by Molmil](/molmil-images/mine/4ww2) | Crystal structure of human TCR Alpha Chain-TRAV21-TRAJ8, Beta Chain-TRBV7-8, Antigen-presenting glycoprotein CD1d, and Beta-2-microglobulin | 分子名称: | (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ... | 著者 | Le Nours, J, Praveena, T, Pellicci, D, Gherardin, N.A, Lim, R.T, Besra, G, Keshipeddy, S, Richardson, S.K, Howell, A.R, Gras, S, Godfrey, D.I, Rossjohn, J, Uldrich, A.P. | 登録日 | 2014-11-10 | 公開日 | 2016-02-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens. Nat Commun, 7, 2016
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7NMG
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![BU of 7nmg by Molmil](/molmil-images/mine/7nmg) | Human MHC Class I, A24 Allele presenting LWM, Complex with 4C6 TCR | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Diabetes epitope LWMRLLPLL, ... | 著者 | Rizkallah, P.J, Sewell, A.K, Cole, D.K, Wall, A. | 登録日 | 2021-02-23 | 公開日 | 2022-09-07 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Human MHC Class I, A24 Allele presenting LWM, Complex with 4C6 TCR To Be Published
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8GQW
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![BU of 8gqw by Molmil](/molmil-images/mine/8gqw) | The Crystal Structures of a Swine SLA-2*HB01 Molecules Complexed with a CTL epitope from Asia1 serotype of Foot-and-mouth disease virus | 分子名称: | Hu64, MHC class I antigen, beta 2 microglobulin | 著者 | Feng, L, Gao, Y.Y, Sun, M.W, Li, Z.B, Zhang, Q, Yang, J, Qiao, C, Jin, H, Feng, H.S, Xian, Y.H, Qi, J.X, Gao, G.F, Liu, W.J, Gao, F.S. | 登録日 | 2022-08-31 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | The Parallel Presentation of Two Functional CTL Epitopes Derived from the O and Asia 1 Serotypes of Foot-and-Mouth Disease Virus and Swine SLA-2*HB01: Implications for Universal Vaccine Development. Cells, 11, 2022
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8ISN
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![BU of 8isn by Molmil](/molmil-images/mine/8isn) | HLA-A24 in complex with modified 9mer WT1 peptide | 分子名称: | Beta-2-microglobulin, CYS-TYR-THR-TRP-ASN-GLN-MET-ASN-LEU, GLYCEROL, ... | 著者 | Bekker, G.J, Numoto, N, Kawasaki, M, Hayashi, T, Yabuno, S, Kozono, Y, Shimizu, T, Kozono, H, Ito, N, Oda, M, Kamiya, N. | 登録日 | 2023-03-21 | 公開日 | 2023-09-13 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Elucidation of binding mechanism, affinity, and complex structure between mWT1 tumor-associated antigen peptide and HLA-A*24:02. Protein Sci., 32, 2023
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4I2X
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![BU of 4i2x by Molmil](/molmil-images/mine/4i2x) | Crystal structure of Signal Regulatory Protein gamma (SIRP-gamma) in complex with FabOX117 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, FabOX117 heavy chain, ... | 著者 | Nettleship, J.E, Ren, J, Stuart, D.I, Owens, R.J, Oxford Protein Production Facility (OPPF) | 登録日 | 2012-11-23 | 公開日 | 2013-12-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Crystal structure of signal regulatory protein gamma (SIRP gamma) in complex with an antibody Fab fragment. Bmc Struct.Biol., 13, 2013
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6AYN
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![BU of 6ayn by Molmil](/molmil-images/mine/6ayn) | |
6AZL
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![BU of 6azl by Molmil](/molmil-images/mine/6azl) | |
6AU5
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![BU of 6au5 by Molmil](/molmil-images/mine/6au5) | |
6AXP
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![BU of 6axp by Molmil](/molmil-images/mine/6axp) | |
4D9L
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![BU of 4d9l by Molmil](/molmil-images/mine/4d9l) | Fab structure of anti-HIV-1 gp120 V2 mAb 697 | 分子名称: | Heavy chain of Fab fragment of anti-HIV1 gp120 V2 mAb 697, Light chain of Fab fragment of anti-HIV1 gp120 V2 mAb 697 | 著者 | Pan, R.M, Kong, X.P. | 登録日 | 2012-01-11 | 公開日 | 2012-03-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.485 Å) | 主引用文献 | Functional and immunochemical cross-reactivity of V2-specific monoclonal antibodies from HIV-1-infected individuals. Virology, 427, 2012
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6WOL
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![BU of 6wol by Molmil](/molmil-images/mine/6wol) | Next generation monomeric IgG4 Fc bound to neonatal Fc receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, IgG receptor FcRn large subunit p51, ... | 著者 | Oganesyan, V.Y, Shan, L, van Dyk, N, Dall'Acqua, W.F. | 登録日 | 2020-04-24 | 公開日 | 2021-09-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | In vivo pharmacokinetic enhancement of monomeric Fc and monovalent bispecific designs through structural guidance. Commun Biol, 4, 2021
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7SR3
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![BU of 7sr3 by Molmil](/molmil-images/mine/7sr3) | |
6R2U
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![BU of 6r2u by Molmil](/molmil-images/mine/6r2u) | Zinc-alpha2-Glycoprotein with a Fluorescent Dansyl C 11 Fatty Acid | 分子名称: | 11-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)undecanoic acid, AZIDE ION, SULFATE ION, ... | 著者 | Lau, A.M, Gor, J, Perkins, S.J, Coker, A.R, McDermott, L.C. | 登録日 | 2019-03-18 | 公開日 | 2019-09-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Crystal structure of zinc-alpha 2-glycoprotein in complex with a fatty acid reveals multiple different modes of protein-lipid binding. Biochem.J., 476, 2019
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5IB5
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![BU of 5ib5 by Molmil](/molmil-images/mine/5ib5) | Crystal structure of HLA-B*27:09 complexed with the self-peptide pVIPR and Copper | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, COPPER (II) ION, ... | 著者 | Janke, R, Ballaschk, M, Schmieder, P, Uchanska-Ziegler, B, Ziegler, A, Loll, B. | 登録日 | 2016-02-22 | 公開日 | 2017-02-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype. J.Biol.Chem., 2019
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2WNG
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![BU of 2wng by Molmil](/molmil-images/mine/2wng) | complete extracellular structure of human signal regulatory protein (SIRP) alpha | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 | 著者 | Hatherley, D, Graham, S.C, Harlos, K, Stuart, D.I, Barclay, A.N. | 登録日 | 2009-07-09 | 公開日 | 2009-07-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Structure of Signal-Regulatory Protein Alpha: A Link to Antigen Receptor Evolution. J.Biol.Chem., 284, 2009
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3TBS
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![BU of 3tbs by Molmil](/molmil-images/mine/3tbs) | CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX THE WITH LCMV-DERIVED GP33 ALTERED PEPTIDE ligand (V3P,Y4A) | 分子名称: | Beta-2-microglobulin, GLYCEROL, GLYCOPROTEIN G1, ... | 著者 | Duru, A.D, Allerbring, E.B, Uchtenhagen, H, Mazumdar, P.A, Badia-Martinez, D, Madhurantakam, C, Sandalova, T, Nygren, P, Achour, A. | 登録日 | 2011-08-08 | 公開日 | 2012-08-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Conversion of a T cell viral antagonist into an agonist through higher stabilization and conserved molecular mimicry: Implications for TCR recognition To be Published
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4ACP
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![BU of 4acp by Molmil](/molmil-images/mine/4acp) | Deactivation of human IgG1 Fc by endoglycosidase treatment | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IG GAMMA-1 CHAIN C REGION | 著者 | Raman, K, Bowden, T.A, Krishna, B.A, Dwek, R.A, Crispin, M, Scanlan, C.N. | 登録日 | 2011-12-16 | 公開日 | 2012-04-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Selective Deactivation of Serum Igg: A General Strategy for the Enhancement of Monoclonal Antibody Receptor Interactions. J.Mol.Biol., 420, 2012
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8J4G
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![BU of 8j4g by Molmil](/molmil-images/mine/8j4g) | |
6AMT
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![BU of 6amt by Molmil](/molmil-images/mine/6amt) | |
4R26
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![BU of 4r26 by Molmil](/molmil-images/mine/4r26) | Crystal structure of human Fab PGT124, a broadly neutralizing and potent HIV-1 neutralizing antibody | 分子名称: | GLYCEROL, PGR124-Light Chain, PGT124-Heavy Chain | 著者 | Garces, F, Kong, L, Wilson, I.A. | 登録日 | 2014-08-08 | 公開日 | 2014-10-08 | 最終更新日 | 2017-06-21 | 実験手法 | X-RAY DIFFRACTION (2.4969 Å) | 主引用文献 | Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies. Cell(Cambridge,Mass.), 159, 2014
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