8ISN

HLA-A24 in complex with modified 9mer WT1 peptide

Summary for 8ISN

• Entry DOI: 10.2210/pdb8isn/pdb
• Descriptor: MHC class I antigen, Beta-2-microglobulin, CYS-TYR-THR-TRP-ASN-GLN-MET-ASN-LEU, ... (6 entities in total)
• Functional Keywords: immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 96854.83

Authors

Bekker, G.J.,Numoto, N.,Kawasaki, M.,Hayashi, T.,Yabuno, S.,Kozono, Y.,Shimizu, T.,Kozono, H.,Ito, N.,Oda, M.,Kamiya, N. (deposition date: 2023-03-21, release date: 2023-09-13, Last modification date: 2023-10-25)

• Primary citation: Bekker, G.J.,Numoto, N.,Kawasaki, M.,Hayashi, T.,Yabuno, S.,Kozono, Y.,Shimizu, T.,Kozono, H.,Ito, N.,Oda, M.,Kamiya, N.; Elucidation of binding mechanism, affinity, and complex structure between mWT1 tumor-associated antigen peptide and HLA-A*24:02.; Protein Sci., 32:e4775-e4775, 2023; PubMed: 37661929; DOI: 10.1002/pro.4775

Experimental method

X-RAY DIFFRACTION (2.48 Å)