8ISN

HLA-A24 in complex with modified 9mer WT1 peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	MHC class I antigen	polymer	305	34902.3	2	UniProt (D9UAY1) Pfam (PF00129) Pfam (PF07654)	Homo sapiens (human)
2	B, E (B, E)	Beta-2-microglobulin	polymer	99	11748.2	2	UniProt (P61769) Pfam (PF07654)	Homo sapiens (human)
3	C, F (C, F)	CYS-TYR-THR-TRP-ASN-GLN-MET-ASN-LEU	polymer	9	1172.3	2	UniProt (by SIFTS) (P19544)	Homo sapiens
4	G (G)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
5	H, I, J, K, L (A, B)	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
6	M, N, O, P, Q (A, B, C, D, E)	water	water		18.0	153	Chemie (HOH)

Sequence modifications

A, D: 1 - 276 (UniProt: D9UAY1)

PDB	External Database	Details
Gly 277	-	expression tag
Ala 278	-	expression tag
Ser 279	-	expression tag
Gly 280	-	expression tag
Asp 281	-	expression tag
Tyr 282	-	expression tag
Lys 283	-	expression tag
Asp 284	-	expression tag
Asp 285	-	expression tag
Asp 286	-	expression tag
Asp 287	-	expression tag
Lys 288	-	expression tag
Gly 289	-	expression tag
Gly 290	-	expression tag
Gly 291	-	expression tag
Gly 292	-	expression tag
Leu 293	-	expression tag
Asn 294	-	expression tag
Asp 295	-	expression tag
Ile 296	-	expression tag
Phe 297	-	expression tag
Glu 298	-	expression tag
Ala 299	-	expression tag
Gln 300	-	expression tag
Lys 301	-	expression tag
Ile 302	-	expression tag
Glu 303	-	expression tag
Trp 304	-	expression tag
His 305	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	95645.7
Branched	Number of molecules	1
	Total formula weight	748.7
Non-Polymers*	Number of molecules	5
	Total formula weight	460.5
All*	Total formula weight	96854.8

*Water molecules are not included.