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2N35
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BU of 2n35 by Molmil
Fusion to a Highly Stable Consensus Albumin Binding Domain Allows for Tunable Pharmacokinetics
分子名称: Albumin binding protein
著者Gibbs, A.C, Jacobs, S.A.
登録日2015-05-21
公開日2015-09-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Fusion to a highly stable consensus albumin binding domain allows for tunable pharmacokinetics.
Protein Eng.Des.Sel., 28, 2015
2N8D
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BU of 2n8d by Molmil
In silico designed antimicrobial peptide Lavracin
分子名称: antimicrobial peptide Lavracin
著者Pillong, M, Blatter, M, Schneider, G.
登録日2015-10-13
公開日2017-01-18
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Rational Design of Membrane-Pore-Forming Peptides.
Small, 13, 2017
4N6T
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BU of 4n6t by Molmil
Adhiron: a stable and versatile peptide display scaffold - full length adhiron
分子名称: Adhiron
著者Mcpherson, M, Tomlinson, D, Owen, R.L, Nettleship, J.E, Owens, R.J.
登録日2013-10-14
公開日2014-04-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications.
Protein Eng.Des.Sel., 27, 2014
6Z1K
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BU of 6z1k by Molmil
A de novo Enzyme for the Morita-Baylis-Hillman Reaction BH32.6
分子名称: 1,2-ETHANEDIOL, BH32.6 protein, CALCIUM ION, ...
著者Levy, C.W.
登録日2020-05-13
公開日2021-08-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Engineering an efficient and enantioselective enzyme for the Morita-Baylis-Hillman reaction.
Nat.Chem., 14, 2022
6Z1L
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BU of 6z1l by Molmil
A de novo Enzyme for the Morita-Baylis-Hillman Reaction BH32.12
分子名称: 1,2-ETHANEDIOL, BH32.12 protein, PHOSPHATE ION
著者Levy, C.W.
登録日2020-05-13
公開日2021-08-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Engineering an efficient and enantioselective enzyme for the Morita-Baylis-Hillman reaction.
Nat.Chem., 14, 2022
3PFD
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BU of 3pfd by Molmil
Crystal structure of an Acyl-CoA dehydrogenase from Mycobacterium thermoresistibile bound to reduced flavin adenine dinucleotide solved by combined iodide ion SAD MR
分子名称: Acyl-CoA dehydrogenase, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, IODIDE ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-10-28
公開日2010-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献SAD phasing using iodide ions in a high-throughput structural genomics environment.
J.STRUCT.FUNCT.GENOM., 12, 2011
6B6H
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BU of 6b6h by Molmil
The cryo-EM structure of a bacterial class I transcription activation complex
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Liu, B, Hong, C, Huang, R, Yu, Z, Steitz, T.A.
登録日2017-10-02
公開日2017-11-15
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of bacterial transcription activation.
Science, 358, 2017
3TES
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BU of 3tes by Molmil
Crystal Structure of Tencon
分子名称: Tencon
著者Luo, J, Jacobs, S, Teplyakov, A, Obmolova, G, O'Neil, K, Gilliland, G.
登録日2011-08-15
公開日2012-05-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Design of novel FN3 domains with high stability by a consensus sequence approach.
Protein Eng.Des.Sel., 25, 2012
6C7T
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BU of 6c7t by Molmil
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 20 round 5
分子名称: Kemp Eliminase KE07
著者Jackson, C.J, Hong, N.-S, Carr, P.D.
登録日2018-01-23
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9, 2018
6CAI
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BU of 6cai by Molmil
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 24 round 7
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Kemp Eliminase KE07
著者Jackson, C.J, Hong, N.-S, Carr, P.D.
登録日2018-01-30
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9, 2018
6C8B
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BU of 6c8b by Molmil
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 23 round 6
分子名称: Kemp eliminase KE07
著者Jackson, C.J, Hong, N.-S, Carr, P.D.
登録日2018-01-24
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9, 2018
5WKP
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BU of 5wkp by Molmil
Crystal Structure of the Human mitochondrial Cysteine Desulfurase in complex with ISD11 and Iron-Sulfur Cluster Scaffold Protein ISCU1, and E. coli ACP1 protein at 3.15A
分子名称: Acyl carrier protein, Cysteine desulfurase, mitochondrial, ...
著者Boniecki, M.T, Cygler, M.
登録日2017-07-25
公開日2017-11-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex.
Nat Commun, 8, 2017
6DKV
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BU of 6dkv by Molmil
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 21 round 5
分子名称: 5-nitro-2-oxidanyl-benzenecarbonitrile, DI(HYDROXYETHYL)ETHER, Kemp eliminase KE07
著者Jackson, C.J, Hong, N.-S, Carr, P.D.
登録日2018-05-30
公開日2018-08-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9, 2018
6C7H
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BU of 6c7h by Molmil
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 18 Design Trp50Ala mutant
分子名称: Kemp eliminase KE07
著者Jackson, C.J, Hong, N.-S, Carr, P.D.
登録日2018-01-22
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9, 2018
6C7M
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BU of 6c7m by Molmil
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 19 round 5
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Kemp Eliminase KE07
著者Jackson, C.J, Hong, N.-S, Carr, P.D.
登録日2018-01-22
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9, 2018
6C7V
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BU of 6c7v by Molmil
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 22 round 5
分子名称: Kemp eliminase KE07
著者Jackson, C.J, Hong, N.-S, Carr, P.D.
登録日2018-01-23
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9, 2018
5WLW
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BU of 5wlw by Molmil
Crystal Structure of the Human Mitochondrial Cysteine Desulfurase with active Cysteine Loop within ISCU1 active site, coordinating Zn ion. Complexed with human ISD11 and E. coli ACP1 at 3.3A.
分子名称: Acyl carrier protein, Cysteine desulfurase, mitochondrial, ...
著者Boniecki, M.T, Cygler, M.
登録日2017-07-27
公開日2017-11-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.317 Å)
主引用文献Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex.
Nat Commun, 8, 2017
3TEU
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BU of 3teu by Molmil
Crystal structure of fibcon
分子名称: 1,4-DIETHYLENE DIOXIDE, Fibcon
著者Luo, J, Jacobs, S, Teplyakov, A, Obmolova, G, O'Neil, K, Gilliland, G.
登録日2011-08-15
公開日2012-05-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.002 Å)
主引用文献Design of novel FN3 domains with high stability by a consensus sequence approach.
Protein Eng.Des.Sel., 25, 2012
6DC1
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BU of 6dc1 by Molmil
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 25 round 7
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-nitro-2-oxidanyl-benzenecarbonitrile, ...
著者Jackson, C.J, Hong, N.-S, Carr, P.D.
登録日2018-05-03
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9, 2018
6DNJ
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BU of 6dnj by Molmil
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 28 round 5
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-nitro-1,2-benzoxazole, Kemp eliminase KE07
著者Jackson, C.J, Hong, N.-S, Carr, P.D.
登録日2018-06-06
公開日2018-08-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9, 2018
6CT3
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BU of 6ct3 by Molmil
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 27 round 7-2
分子名称: 5-nitro-2-oxidanyl-benzenecarbonitrile, GLYCEROL, Kemp eliminase, ...
著者Jackson, C.J, Hong, N.-S, Carr, P.D.
登録日2018-03-22
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The evolution of multiple active site configurations in a designed enzyme.
Nat Commun, 9, 2018
7T03
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BU of 7t03 by Molmil
NMR structure of a designed cold unfolding four helix bundle
分子名称: Cold unfolding four helix bundle
著者Pulavarti, S, Szyperski, T, Yuen, S, Maguire, J, Griffin, J, Kuhlman, B.
登録日2021-11-29
公開日2022-03-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献From Protein Design to the Energy Landscape of a Cold Unfolding Protein.
J.Phys.Chem.B, 126, 2022
1SOO
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BU of 1soo by Molmil
ADENYLOSUCCINATE SYNTHETASE INHIBITED BY HYDANTOCIDIN 5'-MONOPHOSPHATE
分子名称: ADENYLOSUCCINATE SYNTHETASE, BETA-MERCAPTOETHANOL, HYDANTOCIDIN-5'-PHOSPHATE, ...
著者Cowan-Jacob, S.W.
登録日1996-05-07
公開日1997-09-04
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The mode of action and the structure of a herbicide in complex with its target: binding of activated hydantocidin to the feedback regulation site of adenylosuccinate synthetase.
Proc.Natl.Acad.Sci.USA, 93, 1996
1SON
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BU of 1son by Molmil
ADENYLOSUCCINATE SYNTHETASE IN COMPLEX WITH THE NATURAL FEEDBACK INHIBITOR AMP
分子名称: ADENOSINE MONOPHOSPHATE, ADENYLOSUCCINATE SYNTHETASE, BETA-MERCAPTOETHANOL
著者Cowan-Jacob, S.W.
登録日1996-05-07
公開日1997-09-04
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The mode of action and the structure of a herbicide in complex with its target: binding of activated hydantocidin to the feedback regulation site of adenylosuccinate synthetase.
Proc.Natl.Acad.Sci.USA, 93, 1996
1P9B
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BU of 1p9b by Molmil
Structure of fully ligated Adenylosuccinate synthetase from Plasmodium falciparum
分子名称: 6-O-PHOSPHORYL INOSINE MONOPHOSPHATE, Adenylosuccinate Synthetase, GUANOSINE-5'-DIPHOSPHATE, ...
著者Eaazhisai, K, Jayalakshmi, R, Gayathri, P, Anand, R.P, Sumathy, K, Balaram, H, Murthy, M.R.
登録日2003-05-10
公開日2004-02-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Fully Ligated Adenylosuccinate Synthetase from Plasmodium falciparum.
J.Mol.Biol., 335, 2004

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