1SON

ADENYLOSUCCINATE SYNTHETASE IN COMPLEX WITH THE NATURAL FEEDBACK INHIBITOR AMP

Summary for 1SON

Entry DOI	10.2210/pdb1son/pdb
Descriptor	ADENYLOSUCCINATE SYNTHETASE, ADENOSINE MONOPHOSPHATE, BETA-MERCAPTOETHANOL, ... (4 entities in total)
Functional Keywords	purine nucleotide biosynthesis, gtp-hydrolyzing enzyme, herbicide, ligase, synthetase
Biological source	Escherichia coli
Cellular location	Cytoplasm: P0A7D4
Total number of polymer chains	1
Total formula weight	47694.95
Authors	Cowan-Jacob, S.W. (deposition date: 1996-05-07, release date: 1997-09-04, Last modification date: 2023-08-09)
Primary citation	Fonne-Pfister, R.,Chemla, P.,Ward, E.,Girardet, M.,Kreuz, K.E.,Honzatko, R.B.,Fromm, H.J.,Schar, H.P.,Grutter, M.G.,Cowan-Jacob, S.W. The mode of action and the structure of a herbicide in complex with its target: binding of activated hydantocidin to the feedback regulation site of adenylosuccinate synthetase. Proc.Natl.Acad.Sci.USA, 93:9431-9436, 1996 Cited by PubMed: 8790347 DOI: 10.1073/pnas.93.18.9431 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation