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1NPB
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BU of 1npb by Molmil
Crystal structure of the fosfomycin resistance protein from transposon Tn2921
分子名称: GLYCEROL, SULFATE ION, fosfomycin-resistance protein
著者Pakhomova, S, Rife, C.L, Armstrong, R.N, Newcomer, M.E.
登録日2003-01-17
公開日2004-03-02
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of fosfomycin resistance protein FosA from transposon Tn2921.
Protein Sci., 13, 2004
1NT2
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BU of 1nt2 by Molmil
CRYSTAL STRUCTURE OF FIBRILLARIN/NOP5P COMPLEX
分子名称: Fibrillarin-like pre-rRNA processing protein, S-ADENOSYLMETHIONINE, conserved hypothetical protein
著者Aittaleb, M, Rashid, R, Chen, Q, Palmer, J.R, Daniels, C.J, Li, H.
登録日2003-01-28
公開日2003-04-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure and function of archaeal box C/D sRNP core proteins.
Nat.Struct.Biol., 10, 2003
4LYE
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BU of 4lye by Molmil
Crystal structure of the S105A mutant of a C-C hydrolase, DxnB2 from Sphingomonas wittichii RW1, in complex with substrate HOPDA
分子名称: (3E)-2,6-DIOXO-6-PHENYLHEX-3-ENOATE, MCP Hydrolase
著者Ghosh, S, Bolin, J.T.
登録日2013-07-31
公開日2013-10-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献A substrate-assisted mechanism of nucleophile activation in a ser-his-asp containing C-C bond hydrolase.
Biochemistry, 52, 2013
1NX6
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BU of 1nx6 by Molmil
Crystal Structure of Aspartate Semialdehyde Dehydrogenase from Haemophilus influenzae as a Tetrahedral Hemithiocetal Reaction intermediate with Phosphate at 2.15 A
分子名称: Aspartate-Semialdehyde Dehydrogenase, PHOSPHATE ION
著者Blanco, J, Moore, R.A, Viola, R.E.
登録日2003-02-09
公開日2003-11-04
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Capture of an Intermediate in the Catalytic Cycle of L-Aspartate-beta-Semialdehyde Dehydrogenase
Proc.Natl.Acad.Sci.USA, 100, 2003
3GL2
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BU of 3gl2 by Molmil
Crystal structure of dicamba monooxygenase bound to dicamba
分子名称: 3,6-dichloro-2-methoxybenzoic acid, DdmC, FE (III) ION, ...
著者Wilson, M.A, Dumitru, R, Jiang, W.Z, Weeks, D.P.
登録日2009-03-11
公開日2009-08-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of dicamba monooxygenase: a Rieske nonheme oxygenase that catalyzes oxidative demethylation.
J.Mol.Biol., 392, 2009
3CXW
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BU of 3cxw by Molmil
Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a beta carboline ligand I
分子名称: (4R)-7,8-dichloro-1',9-dimethyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile, CHLORIDE ION, Pimtide peptide, ...
著者Filippakopoulos, P, Bullock, A, Fedorov, O, Huber, K, Bracher, F, Pike, A.C.W, Roos, A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2008-04-25
公開日2008-07-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献7,8-Dichloro-1-oxo-beta-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes
J.Med.Chem., 55, 2012
3GPH
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BU of 3gph by Molmil
Human cytochrome P450 2E1 in complex with omega-imidazolyl-decanoic acid
分子名称: 10-(1H-imidazol-1-yl)decanoic acid, Cytochrome P450 2E1, PROTOPORPHYRIN IX CONTAINING FE
著者Porubsky, P.R, Battaile, K.P, Scott, E.E.
登録日2009-03-23
公開日2010-05-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Human cytochrome P450 2E1 structures with fatty acid analogs reveal a previously unobserved binding mode.
J.Biol.Chem., 285, 2010
2XWJ
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BU of 2xwj by Molmil
Crystal Structure of Complement C3b in Complex with Factor B
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 ALPHA CHAIN, COMPLEMENT C3 BETA CHAIN, ...
著者Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P.
登録日2010-11-04
公開日2011-01-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
4NO6
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BU of 4no6 by Molmil
yCP in complex with Z-Leu-Leu-Leu-vinylsulfone
分子名称: MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(3S)-5-methyl-1-(methylsulfonyl)hexan-3-yl]-L-leucinamide, Probable proteasome subunit alpha type-7, ...
著者Stein, M.L, Cui, H, Beck, P, Dubiella, C, Voss, C, Krueger, A, Schmidt, B, Groll, M.
登録日2013-11-19
公開日2014-02-12
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the alpha-Ketoamide Electrophile as an Auspicious Reversible Lead Motif.
Angew.Chem.Int.Ed.Engl., 53, 2014
7M2U
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BU of 7m2u by Molmil
Nucleotide Excision Repair complex TFIIH Rad4-33
分子名称: CALCIUM ION, DNA repair helicase RAD25, DNA repair helicase RAD3, ...
著者van Eeuwen, T, Murakami, K.
登録日2021-03-17
公開日2021-07-28
実験手法ELECTRON MICROSCOPY (8.2 Å)
主引用文献Cryo-EM structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in nucleotide excision repair.
Nat Commun, 12, 2021
3GQ9
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BU of 3gq9 by Molmil
Crystal Structure of the Bacteriophage phi29 gene product 12 N-terminal fragment in an apo form
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Preneck appendage protein, SODIUM ION
著者Xiang, Y, Rossmann, M.G.
登録日2009-03-24
公開日2009-05-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystallographic insights into the autocatalytic assembly mechanism of a bacteriophage tail spike.
Mol.Cell, 34, 2009
3D7K
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BU of 3d7k by Molmil
Crystal structure of benzaldehyde lyase in complex with the inhibitor MBP
分子名称: 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-{(S)-hydroxy[(R)-hydroxy(methoxy)phosphoryl]phenylmethyl}-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, Benzaldehyde lyase, CALCIUM ION
著者Brandt, G.S.
登録日2008-05-21
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Probing the active center of benzaldehyde lyase with substitutions and the pseudosubstrate analogue benzoylphosphonic acid methyl ester
Biochemistry, 47, 2008
4NE2
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BU of 4ne2 by Molmil
Pantothenamide-bound Pantothenate Kinase from Klebsiella pneumoniae
分子名称: (R)-N-(3-((2-(benzo[d][1,3]dioxol-5-yl)ethyl)amino)-3-oxopropyl)-2,4-dihydroxy-3,3-dimethylbutanamide, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Hughes, S.J, Antoshchenko, T, Kim, K.P, Smil, D, Park, H.W.
登録日2013-10-28
公開日2014-02-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural characterization of a new N-substituted pantothenamide bound to pantothenate kinases from Klebsiella pneumoniae and Staphylococcus aureus.
Proteins, 82, 2014
2XWB
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BU of 2xwb by Molmil
Crystal Structure of Complement C3b in complex with Factors B and D
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3B ALPHA' CHAIN, ...
著者Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P.
登録日2010-11-01
公開日2011-01-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
7M5O
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BU of 7m5o by Molmil
Cryo-EM structure of CasPhi-2 (Cas12j) bound to crRNA
分子名称: CasPhi, ZINC ION, crRNA
著者Pausch, P, Soczek, K, Nogales, E, Doudna, J.
登録日2021-03-24
公開日2021-08-04
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献DNA interference states of the hypercompact CRISPR-Cas Phi effector.
Nat.Struct.Mol.Biol., 28, 2021
5HGP
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BU of 5hgp by Molmil
Hexameric HIV-1 CA in complex with hexacarboxybenzene
分子名称: BENZENE HEXACARBOXYLIC ACID, Capsid protein P24
著者Jacques, D.A, James, L.C.
登録日2016-01-08
公開日2016-10-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis.
Nature, 536, 2016
3CH3
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BU of 3ch3 by Molmil
Crystal Structure Analysis of SERA5E from plasmodium falciparum
分子名称: DIHYDROGENPHOSPHATE ION, POTASSIUM ION, Serine-repeat antigen protein
著者Smith, B.J, Malby, R.L, Colman, P.M, Clarke, O.B.
登録日2008-03-07
公開日2008-03-25
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural Insights into the Protease-like Antigen Plasmodium falciparum SERA5 and Its Noncanonical Active-Site Serine
J.Mol.Biol., 392, 2009
7M5M
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BU of 7m5m by Molmil
PCNA bound to peptide mimetic
分子名称: N-BUTANE, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen
著者Vandborg, B.A, Bruning, J.B.
登録日2021-03-24
公開日2021-08-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A cell permeable bimane-constrained PCNA-interacting peptide.
Rsc Chem Biol, 2, 2021
5HHM
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BU of 5hhm by Molmil
Crystal Structure of the JM22 TCR in complex with HLA-A*0201 in complex with M1-F5L
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Gras, S, Josephs, T.M, Rossjohn, J.
登録日2016-01-11
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses.
Proc.Natl.Acad.Sci.USA, 113, 2016
3GUT
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BU of 3gut by Molmil
Crystal structure of a higher-order complex of p50:RelA bound to the HIV-1 LTR
分子名称: HIV-LTR Core Forward Strand, HIV-LTR Core Reverse Strand, Nuclear factor NF-kappa-B p105 subunit, ...
著者Stroud, J.C, Oltman, A.J, Han, A, Bates, D.L, Chen, L.
登録日2009-03-30
公開日2009-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.59 Å)
主引用文献Structural basis of HIV-1 activation by NF-kappaB--a higher-order complex of p50:RelA bound to the HIV-1 LTR.
J.Mol.Biol., 393, 2009
1Q6Q
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BU of 1q6q by Molmil
Structure of 3-keto-L-gulonate 6-phosphate decarboxylase with bound xylitol 5-phosphate
分子名称: 3-keto-L-gulonate 6-phosphate decarboxylase, L-XYLITOL 5-PHOSPHATE, MAGNESIUM ION
著者Wise, E.L, Yew, W.S, Gerlt, J.A, Rayment, I.
登録日2003-08-13
公開日2003-10-28
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.695 Å)
主引用文献Structural Evidence for a 1,2-Enediolate Intermediate in the Reaction Catalyzed by 3-Keto-l-Gulonate 6-Phosphate Decarboxylase, a Member of the Orotidine 5'-Monophosphate Decarboxylase Suprafamily
Biochemistry, 42, 2003
7M8E
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BU of 7m8e by Molmil
E.coli RNAP-RapA elongation complex
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Shi, W, Liu, B.
登録日2021-03-29
公開日2021-08-18
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for activation of Swi2/Snf2 ATPase RapA by RNA polymerase.
Nucleic Acids Res., 49, 2021
4NO1
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BU of 4no1 by Molmil
yCP in complex with Z-Leu-Leu-Leu-B(OH)2
分子名称: MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(1R)-1-(dihydroxyboranyl)-3-methylbutyl]-L-leucinamide, Probable proteasome subunit alpha type-7, ...
著者Stein, M.L, Cui, H, Beck, P, Dubiella, C, Voss, C, Krueger, A, Schmidt, B, Groll, M.
登録日2013-11-19
公開日2014-02-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the alpha-Ketoamide Electrophile as an Auspicious Reversible Lead Motif.
Angew.Chem.Int.Ed.Engl., 53, 2014
3GL0
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BU of 3gl0 by Molmil
Crystal structure of dicamba monooxygenase bound to 3,6 dichlorosalicylic acid (DCSA)
分子名称: 1,2-ETHANEDIOL, 3,6-dichloro-2-hydroxybenzoic acid, DdmC, ...
著者Wilson, M.A, Dumitru, R, Jiang, W.Z, Weeks, D.P.
登録日2009-03-11
公開日2009-08-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of dicamba monooxygenase: a Rieske nonheme oxygenase that catalyzes oxidative demethylation.
J.Mol.Biol., 392, 2009
1Q93
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Crystal structure of a mutant of the sarcin/ricin domain from rat 28S rRNA
分子名称: SODIUM ION, SULFATE ION, Sarcin/Ricin 28S rRNA
著者Correll, C.C, Beneken, J, Plantinga, M.J, Lubbers, M, Chan, Y.L.
登録日2003-08-22
公開日2003-11-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The common and distinctive features of the bulged-G motif based on a 1.04 A resolution RNA structure
Nucleic Acids Res., 31, 2003

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