4LYE

Crystal structure of the S105A mutant of a C-C hydrolase, DxnB2 from Sphingomonas wittichii RW1, in complex with substrate HOPDA

Summary for 4LYE

Entry DOI	10.2210/pdb4lye/pdb
Related	4LXG 4LXH 4LXI 4LYD
Descriptor	MCP Hydrolase, (3E)-2,6-DIOXO-6-PHENYLHEX-3-ENOATE (3 entities in total)
Functional Keywords	meta-cleavage product hydrolase, c-c bond hydrolase, alpha-beta hydrolase, dibenzo-p-dioxin degradation, dibenzofuran degradation, hydrolase
Biological source	Sphingomonas wittichii
Total number of polymer chains	1
Total formula weight	30425.73
Authors	Ghosh, S.,Bolin, J.T. (deposition date: 2013-07-31, release date: 2013-10-09, Last modification date: 2024-02-28)
Primary citation	Ruzzini, A.C.,Bhowmik, S.,Ghosh, S.,Yam, K.C.,Bolin, J.T.,Eltis, L.D. A substrate-assisted mechanism of nucleophile activation in a ser-his-asp containing C-C bond hydrolase. Biochemistry, 52:7428-7438, 2013 Cited by PubMed: 24067021 DOI: 10.1021/bi401156a PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.33 Å)

Structure validation