3GUT
Crystal structure of a higher-order complex of p50:RelA bound to the HIV-1 LTR
Summary for 3GUT
Entry DOI | 10.2210/pdb3gut/pdb |
Related | 1P7H 1VKX 2O93 |
Descriptor | Transcription factor p65, Nuclear factor NF-kappa-B p105 subunit, HIV-LTR Core Forward Strand, ... (4 entities in total) |
Functional Keywords | ig fold, protein-dna complex, pseudocontinuous helix, rel family, multiprotein assembly, acetylation, activator, alternative splicing, cytoplasm, dna-binding, nucleus, phosphoprotein, transcription, transcription regulation, ubl conjugation, ank repeat, apoptosis, polymorphism, s-nitrosylation, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q04206 P19838 |
Total number of polymer chains | 12 |
Total formula weight | 295590.26 |
Authors | Stroud, J.C.,Oltman, A.J.,Han, A.,Bates, D.L.,Chen, L. (deposition date: 2009-03-30, release date: 2009-09-08, Last modification date: 2023-09-06) |
Primary citation | Stroud, J.C.,Oltman, A.,Han, A.,Bates, D.L.,Chen, L. Structural basis of HIV-1 activation by NF-kappaB--a higher-order complex of p50:RelA bound to the HIV-1 LTR. J.Mol.Biol., 393:98-112, 2009 Cited by PubMed: 19683540DOI: 10.1016/j.jmb.2009.08.023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.59 Å) |
Structure validation
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