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5HGP

Hexameric HIV-1 CA in complex with hexacarboxybenzene

Summary for 5HGP
Entry DOI10.2210/pdb5hgp/pdb
DescriptorCapsid protein P24, BENZENE HEXACARBOXYLIC ACID (3 entities in total)
Functional Keywordscapsid, viral protein
Biological sourceHuman immunodeficiency virus type 1 (HIV-1)
Cellular locationGag polyprotein: Host cell membrane; Lipid- anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion : P12493
Total number of polymer chains1
Total formula weight25803.44
Authors
Jacques, D.A.,James, L.C. (deposition date: 2016-01-08, release date: 2016-10-19, Last modification date: 2024-01-10)
Primary citationJacques, D.A.,McEwan, W.A.,Hilditch, L.,Price, A.J.,Towers, G.J.,James, L.C.
HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis.
Nature, 536:349-353, 2016
Cited by
PubMed: 27509857
DOI: 10.1038/nature19098
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

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