Crystal Structure of the JM22 TCR in complex with HLA-A*0201 in complex with M1-F5L

Summary for 5HHM
Related5HHN 5HHO 5HHP 5HHQ
DescriptorHLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, M1-F5L, GILGLVFTL, ... (6 entities in total)
Functional Keywordshla a*0201, influenza, m1, tcr, t cell, immune system
Biological sourceHomo sapiens (Human)
Cellular locationMembrane; Single-pass type I membrane protein: P01892
Secreted : P61769
Total number of polymer chains10
Total formula weight188108.82
Gras, S.,Josephs, T.M.,Rossjohn, J. (deposition date: 2016-01-11, release date: 2016-03-23, Last modification date: 2016-05-04)
Primary citationClemens, E.B.,Doherty, P.C.,Grant, E.J.,Gras, S.,Josephs, T.M.,Kedzierska, K.,Miller, A.,Nguyen, T.H.,Price, D.A.,Rossjohn, J.,Thomas, P.G.,Tong, S.Y.,Valkenburg, S.A.,Wang, G.C.
Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses.
Proc.Natl.Acad.Sci.USA, 113:4440-4445, 2016
PubMed: 27036003
DOI: 110.1073/pnas.1603106113
PDB entries with the same primary citation
Experimental method
Structure validation
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PDB entries from 2021-06-23